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CD1C

CD1c molecule

CD1C is a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.

Gene Name: CD1c molecule
Synonyms: CD1C, BDCA1, CD1, CD1c molecule, CD1C antigen, c polypeptide, CD1c antigen, R7
Target Sequences: NM_001765 NP_001756.2 P29017

Publications (2)

1
Splenic proliferative lymphoid nodules distinct from germinal centers are sites of autoantigen stimulation in immune thrombocytopenia. Daridon C, Loddenkemper C, Spieckermann S, Kühl AA, Salama A, Burmester GR, Lipsky PE, Dörner T. Blood. 2012 120:5021-31. (IP; Human) [Full Text Article] [PubMed:22955923]
2
Mycophenolate Mofetil Treatment of Systemic Sclerosis Reduces Myeloid Cell Numbers and Attenuates the Inflammatory Gene Signature in Skin. Mycophenolate Mofetil Treatment of Systemic Sclerosis Reduces Myeloid Cell Numbers and Attenuates the Inflammatory Gene Signature in Skin. The Journal of investigative dermatology. 2018 June;138:1301-1310. [Full Text Article] [PubMed:29391252] [PMC:PMC6590516] Related Antibodies: LS-B10059.

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Antibodies (56)
Proteins (7)
ELISA Kits (1)
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Primary (56)
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CD1C (64)
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rabbit (20)
mouse (35)
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monoclonal mc (35)
polyclonal pc (21)
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CD1C Antibody - Anti-CD1C antibody IHC staining of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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CD1C Mouse anti-Human Monoclonal (4C7) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$440
CD1C Antibody - IHC of paraffin-embedded Human prostate tissue using anti-CD1C mouse monoclonal antibody.
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CD1C Mouse anti-Human Monoclonal (OTI1H9) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CD1C Antibody - IHC of paraffin-embedded Human prostate tissue using anti-CD1C mouse monoclonal antibody.
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CD1C Mouse anti-Human Monoclonal (Carrier-free) (OTI1H9) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CD1C Antibody - Flow cytometry of CD1C antibody This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
CD1C Mouse anti-Human Monoclonal (Azide-free) (M241) Antibody
Human
Flo, IHC, IHC-Fr
Unconjugated, Azide-free
100 µg/$411
CD1C Antibody - Flow cytometry of CD1C antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD1C Mouse anti-Human Monoclonal (FITC) (M241) Antibody
Human
Flo, IHC, IHC-Fr
FITC Conjugated
120 Tests/$446
CD1C Antibody - IHC of paraffin-embedded Human lymphoma tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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CD1C Mouse anti-Human Monoclonal (OTI1F4) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CD1C Antibody - IHC of paraffin-embedded Human lymphoma tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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CD1C Mouse anti-Human Monoclonal (Carrier-free) (OTI1F4) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CD1C Antibody - IHC of paraffin-embedded Human lymphoma tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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CD1C Mouse anti-Human Monoclonal (OTI2D4) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CD1C Antibody - IHC of paraffin-embedded Human lymphoma tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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CD1C Mouse anti-Human Monoclonal (Carrier-free) (OTI2D4) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CD1C Antibody - IHC of paraffin-embedded Human prostate tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Select
CD1C Mouse anti-Human Monoclonal (OTI2B3) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CD1C Antibody - IHC of paraffin-embedded Human prostate tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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CD1C Mouse anti-Human Monoclonal (Carrier-free) (OTI2B3) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
Select
CD1C Mouse anti-Human Monoclonal (Biotin) Antibody
Human
Flo
Biotin Conjugated
100 µg/$626
Select
CD1C Goat anti-Human Polyclonal (aa19-302) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$919
CD1C Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CD1C (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CD1C.
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CD1C Mouse anti-Human Monoclonal (OTI1E10) Antibody
Mouse, Dog, Rat, Human, Monkey
WB
Unconjugated
100 µl/$434
CD1C Antibody - CD1C Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The CD1C antibody detected the CD1C protein (arrow).
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CD1C Rabbit anti-Human Polyclonal (aa226-253) Antibody
Human
WB
Unconjugated
400 µl/$393
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CD1C Mouse anti-Human Monoclonal (3G1B3) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
Select
CD1C Mouse anti-Human Monoclonal (2A7C11) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
CD1C Antibody - Anti-CD1C antibody IHC staining of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
CD1C Mouse anti-Human Monoclonal (Carrier-free) (4C7) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CD1C Antibody - Immunohistochemistry of paraffin-embedded human spleen tissue at dilution 1:100
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CD1C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
CD1C Antibody - IHC of paraffin-embedded Human lymph node tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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CD1C Mouse anti-Human Monoclonal (OTI2F4) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$469
CD1C Antibody - IHC of paraffin-embedded Human lymph node tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
Select
CD1C Mouse anti-Human Monoclonal (Carrier-free) (OTI2F4) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$512
Select
CD1C Mouse anti-Human Monoclonal (L161) Antibody
Human
Flo, IHC, IP
Unconjugated
0.1 mg/$302
CD1C Antibody - Anti-CD1C mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CD1C.
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CD1C Mouse anti-Human Monoclonal (OTI5A8) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
CD1C Antibody - Anti-CD1C mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CD1C.
Select
CD1C Mouse anti-Human Monoclonal (Carrier-free) (OTI5A8) Antibody
Human
IF, WB
Unconjugated, Carrier-free
100 µg/$511
CD1C Antibody - Immunofluorescent analysis of A549 cells diluted at 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Select
CD1C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
Viewing 1-25 of 64 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).