Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
CD1B antibody was raised against human thymocytes and splenic lymphocytes.
Recognizes an epitope distinct from human thymocyte antigen (43kD) that is expressed on the majority of thymocytes and approximately 50% of cases of T ALL. This antibody does not stain Langerhans cells.
Analysis of early stages of T cell differentiation. Immunodiagnosis of certain acute lymphoblastic leukemias and high grade T cell non-Hodgkins lymphomas. Immunoprecipitation studies of the CD1b antigen.
10 mM Sodium Azide, 1 mg/ml BSA
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
CD1B is a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1.