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CD16
CD16 is a low affinity Fc receptor. It is a CD molecule found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. It can be used to isolate populations of these cells by antibodies directed towards CD16, using fluorescent-activated cell sorting or magnetic-activated cell sorting. CD16 has been identified as Fc receptors Fc?RIIIa (CD16a) and Fc?RIIIb (CD16b). These receptors bind to the Fc portion of IgG antibodies which then activates the NK cell for antibody-dependent cell-mediated cytotoxicity. A lack of CD16 in a given population of neutrophils may indicate prematurity, as could be caused by a left-shift due to neutrophilic leukocytosis induced by tissue necrosis or bacterial infection.
CD16 Target Details
| Target Name: | CD16 |
Publications (4)
1
A Csf1r-EGFP Transgene Provides a Novel Marker for Monocyte Subsets in Sheep. Pridans C, Davis GM, Sauter KA, Lisowski ZM, Corripio-Miyar Y, Raper A, Lefevre L, Young R, McCulloch ME, Lillico S, Milne E, Whitelaw B, Hume DA. Journal of immunology (Baltimore, Md. : 1950). 2016 197:2297-305. (Flo; Human)
[Full Text Article]
[PubMed:27521343]
[PMC:PMC5009875]
2
Fatal accelerated rejection with a prominent natural killer cell infiltrate in a heart transplant recipient with peripartum cardiomyopathy. Javaheri A, Wang AR, Luning Prak E, Lal P, Goldberg LR, Kamoun M. Transplant immunology. 2017 (Flo; Human)
[Full Text Article]
[PubMed:29101003]
Related Antibodies: LS-B8501.
3
Intravenous immunoglobulin promotes antitumor responses by modulating macrophage polarization. Domínguez-Soto A, de las Casas-Engel M, Bragado R, Medina-Echeverz J, Aragoneses-Fenoll L, Martín-Gayo E, van Rooijen N, Berraondo P, Toribio ML, Moro MA, Cuartero I, Castrillo A, Sancho D, Sánchez-Torres C, Bruhns P, Sánchez-Ramón S, Corbí AL. Journal of immunology (Baltimore, Md. : 1950). 2014 193:5181-9. (Flo; Human)
[Full Text Article]
[PubMed:25326025]
Related Antibodies: LS-C202099.
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CD16 Mouse anti-Human Monoclonal (DJ130c) Antibody
Human
Flo, IHC, IHC-Fr, IHC-P
Unconjugated
100 µg/$485
CD16 Mouse anti-Human Monoclonal (ASH 1975) Antibody
Mouse, Rat, Human
ELISA, Flo, IF, IHC, IHC-Fr, IP
Unconjugated
100 µg/$493; 500 µg/$669; 1 mg/$1,129
CD16 Rat anti-Human Monoclonal (YFC120.5) Antibody
Human
Flo, IHC, IHC-Fr
Unconjugated
200 µg/$732
CD16 Mouse anti-Human Monoclonal (Biotin) (DJ130c) Antibody
Human
Flo
Biotin Conjugated
25 µg/$281; 0.1 mg/$432
CD16 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Biotin Conjugated
100 Tests/$530
CD16 Mouse Monoclonal (c127) Antibody
Human
IHC, IHC-Fr
Unconjugated
200 µg/$523
CD16 Mouse anti-Human Monoclonal (MEM-154) Antibody
Human
ELISA, Flo, Func, WB
Unconjugated
100 µg/$674
CD16 Mouse anti-Human Monoclonal (Concentrated) (MEM-154) Antibody
Human
Flo, Func, IP, WB
Unconjugated, Concentrated
0.1 mg/$453
CD16 Mouse anti-Human Monoclonal (Concentrated) (TC) (3G8) Antibody
Human
Flo
TC Conjugated, Concentrated
0.5 ml/$625
CD16 Mouse anti-Human Monoclonal Antibody
Human
Flo, IP
Unconjugated
100 µg/$562; 200 µg/$755
CD16 Mouse anti-Human Monoclonal (FITC) (CB16) Antibody
Human
Flo
FITC Conjugated
25 Tests/$270; 100 Tests/$375
CD16 Mouse anti-Pig Monoclonal (FITC) (G7) Antibody
Pig
Flo
FITC Conjugated
100 µg/$962
CD16 Mouse anti-Human Monoclonal (PE) Antibody
Human
Flo, IHC, IHC-Fr
PE Conjugated
120 Tests/$725
CD16 Rabbit anti-Cynomolgus Polyclonal Antibody
Cynomolgus
ELISA, IHC, IHC-P
Unconjugated
100 µl/$412
CD16 Rabbit anti-Human Monoclonal (EP364) Antibody
Human
IHC-Fr, IHC-P
Unconjugated
0.1 ml/$389; 0.5 ml/$556; 1 ml/$885
CD16 Rabbit anti-Human Monoclonal (Ready-to-Use) (EP364) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3 ml/$325; 7 ml/$403; 15 ml/$554
CD16 Rabbit anti-Human Monoclonal (Preservative Free) (221) Antibody
Human
Flo
Unconjugated, Preservative Free
20 µl/$286; 100 µl/$435
CD16 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
Flo
Biotin Conjugated
100 µg/$672
CD16 Mouse anti-Human Monoclonal (PE) (J5511) Antibody
Human
Flo
PE Conjugated
100 Tests/$414
CD16 Mouse anti-Human Monoclonal (PE) Antibody
Human
Flo
PE Conjugated
100 Tests/$755
CD16 Rabbit anti-Human Monoclonal (FITC) (221) Antibody
Human
Flo
FITC Conjugated
25 Tests/$278; 100 Tests/$346
CD16 Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Unconjugated
100 µg/$459
CD16 Mouse anti-Human Monoclonal (GRM1) Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Unconjugated
0.1 mg/$297
CD16 Mouse anti-Human Monoclonal (B338) Antibody
Human
Flo, IF, IHC
Unconjugated
0.2 mg/$328
CD16 Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo, IHC, IHC-Fr, WB
FITC Conjugated
100 Tests/$518
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