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Human CD14 | |
Mouse | |
Human (tested or 100% immunogen sequence identity) | |
IgG2a Monoclonal [UCHM1] | |
Unconjugated | |
Protein A purified | |
Azide-free |
Flow Cytometry |
CD14 antibody was raised against human thymocytes/Sezary T cells. | |
Membrane bond CD14 molecule of about 53 kd. UCHM1 will also immunoprecipitate a soluble form of CD14. | |
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. |
50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride | |
Store at +4°C. Do not freeze. Open under aseptic conditions. | |
For research use only. |
CD14 Antibody, CD14 molecule Antibody, CD14 antigen Antibody
In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.