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Anti-CD14 Antibody (clone UCHM1, Azide-free) LS-C134295

Catalog	Size	Price
LS-C134295-100	100 µg (1 mg/ml)	Unavailable

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Antibody:	Mouse Monoclonal [clone UCHM1] (IgG2a) to Human CD14
Reactivity:	Human
Application:	Flow Cytometry
Format:	Unconjugated, Azide-free

Details

Target:	Human CD14
Host:	Mouse
Reactivity:	Human (tested or 100% immunogen sequence identity)
Clonality:	IgG2a Monoclonal [UCHM1]
Conjugations:	Unconjugated
Purification:	Protein A purified
Modifications:	Azide-free

Applications

Approved:

Flow Cytometry

Specificity and Use

Immunogen:	CD14 antibody was raised against human thymocytes/Sezary T cells.
Specificity:	Membrane bond CD14 molecule of about 53 kd. UCHM1 will also immunoprecipitate a soluble form of CD14.
Usage:	The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Packaging

Presentation:	50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride
Storage:	Store at +4°C. Do not freeze. Open under aseptic conditions.
Restrictions:	For research use only.

About CD14

Uniprot: P08571 NCBI: NM_000591 NP_000582.1

Synonyms: CD14 Antibody, CD14 molecule Antibody, CD14 antigen Antibody

Description: In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.

(More About CD14)

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Date Requested: 10/19/2017

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