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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CD14 Antibody (clone TüK4 (Mab0211)) LS‑C96212
Antibody
CD14 antibody LS-C96212 is an unconjugated mouse monoclonal antibody to human CD14. Validated for IHC.
Catalog
Size
Price
LS-C96212-100
100 µg
Unavailable

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Anti-CD14 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3012 concentration 4 ug/ml.
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Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
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Product Description

CD14 antibody LS-C96212 is an unconjugated mouse monoclonal antibody to human CD14. Validated for IHC.
About CD14
In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. P08571 NM_000591 NP_000582.1

CD14 Antibody, CD14 molecule Antibody, CD14 antigen Antibody


Specifications

Target
CD14
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Monoclonal [TüK4 (Mab0211)]
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen (1:200)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CD14 antibody was raised against human monocytes
Specificity
The antigen is CD14, the receptor for LPS. The epitope has not been further characterized. Antigen distribution: Isolated cells: Positive on granulocytes and monocytes, myeloid leukemia and myeloid cell lines. Tissue sections: Positive on histocytes, Langerhans cells, follicular dendritic cells and high endothelial venules. Specificity: Human: monocytes, granulocytes. Other: not tested.
Presentation
Lyophilized from PBS pH 7.2, 10mg/ml BSA, 0.02% sodium azide
Reconstitution
0.5ml distilled water
Storage
Store at 4°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/21/2018

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