Mouse CD14

Mouse

Mouse (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

biG57

R. Phycoerythrin

Protein G purified

Unmodified

Recombinant mouse CD14.

Recognizes mouse CD14, a 55kD a glycophosphoinositol-linked cell surface protein that also exists in a soluble form. Expression of CD14 is restricted to the myeloid lineage and is predominantly expressed on peripheral blood monocytes, weakly expressed on granulocytes and absent on myeloid progenitors. The CD14 molecule acts as a pattern recognition receptor, which binds lipopolysaccharide (LPS) and other microbial products such as lipoteichoic acid, lipoproteins and peptidoglycan. Binding of LPS to CD14 mediates the innate immune response to LPS and requires the Toll-like receptor-4 (TLR4)/MD-2 complex for effective signalling. Antibodies produced by biG 57 do not inhibit the binding of CD14.

• Flow Cytometry (1:1)

The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

PBS, 0.09% Sodium Azide, 1% BSA

Reconstitute with distilled water.

Store at 4°C. Do not freeze. Store undiluted. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P08571 NCBI: NM_000591 NP_000582.1