Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 2F4/11] (IgG1) to Pig CD11R3
IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
Pig (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [2F4/11]
Protein G purified
IHC - Frozen
Flow Cytometry (1:1 - 1:10)
(applications tested for the base form of this product only)
Specificity and Use
CD11R3 antibody was raised against porcine alveolar macrophages.
Recognizes porcine CD11R3, a 155kD cell surface marker which is a member of the alpha integrin family. CD11R3 has a similar expression pattern to the human CD11b marker, being expressed on granulocytes, monocytes and alveolar macrophages, but not on lymphocytes, eythrocytes or platelets. Clone 2F4/11 is reported to block phagocytosis of complement-opsonized zymosan particles by polymononuclear granulocytes and alveolar macrophages. Removal of sodium azide is recommended prior to use in functional assays -.
The applications listed have been tested for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.
PBS, 0.09% sodium azide, 1% BSA
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles. Protect from light.
Flow cytometry of porcine peripheral blood granulocytes with Mouse anti-Porcine CD11R3. This image was taken for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.
Requested From: United States
Date Requested: 10/26/2016