Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
CD11R3 antibody was raised against porcine alveolar macrophages.
Recognizes porcine CD11R3, a 155kD cell surface marker which is a member of the alpha integrin family. CD11R3 has a similar expression pattern to the human CD11b marker, being expressed on granulocytes, monocytes and alveolar macrophages, but not on lymphocytes, eythrocytes or platelets. Clone 2F4/11 is reported to block phagocytosis of complement-opsonized zymosan particles by polymononuclear granulocytes and alveolar macrophages. Removal of sodium azide is recommended prior to use in functional assays -.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, 0.09% sodium azide, 1% BSA
Short term: +4°C; Long term: -20°C; Avoid freeze-thaw cycles; Protect from light.