Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Western blot (0.1 - 0.2 µg/ml)
ELISA (0.5 - 1 µg/ml)
Specificity and Use
CD109 antibody was raised against cD109 NS0-derived rhCD109.
Recognizes human CD109.
Suitable for use in Direct ELISA and Western Blot. Direct ELISA: 0.5-1 ug/mL detection limit for rhCD109 ~0.3 ng/well. Western Blot: 0.1-0.2 ug/mL detection limit for rhCD109 ~10 ng/lane under non-reducing and reducing conditions.
Lyophilized from PBS, 5% trehalose. Reconstitute, 200 ul 40-50% glycerol, PBS.
CD109 is a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene.