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CCT2 / CCT Beta

chaperonin containing TCP1, subunit 2 (beta)

This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the gene described in this record have been observed but have not been thoroughly characterized.

Gene Name: chaperonin containing TCP1, subunit 2 (beta)
Synonyms: CCT2, 99D8.1, CCT-beta, CCTB, PRO1633, TCP-1-beta, TCP1 Beta
Target Sequences: NM_006431 NP_006422.1 P78371

Publications (3)

1
Targeting chaperonin containing TCP1 (CCT) as a molecular therapeutic for small cell lung cancer. Carr AC, Khaled AS, Bassiouni R, Flores O, Nierenberg D, Bhatti H, Vishnubhotla P, Manuel JP, Santra S, Khaled AR. Oncotarget. 2017 8:110273-110288. (WB; Human) [Full Text Article] [PubMed:29299146] Related Antibodies: LS-B4861.
2
Investigating Chaperonin-Containing TCP-1 subunit 2 as an essential component of the chaperonin complex for tumorigenesis. Anne E Showalter , Ana C Martini , Daniel Nierenberg, Kristen Hosang, Naima Ahmed Fahmi, Priya Gopalan, Amr S Khaled, Wei Zhang, Annette R Khaled. Scientific reports. 2020 Jan;10:798. [Full Text Article] [PubMed:31964905] [PMC:PMC6972895] Related Antibodies: LS-B4861.
3
Chaperonin containing TCP1 as a marker for identification of circulating tumor cells in blood. Amanda Cox, Ana Martini, Heba Ghozlan, Rebecca Moroose, Xiang Zhu, Eunkyung Lee, Amr S Khaled, Louis Barr, Carlos Alemany, Na'im Fanaian, Elizabeth Griffith, Ryan Sause, S A Litherland, Annette R Khaled. PloS one. 2022 June;17:e0264651. [Full Text Article] [PubMed:35749519] [PMC:PMC9232171] Related Antibodies: LS-C649415.

☰ Filters
Antibodies (41)
Proteins (7)
ELISA Kits (2)
Over-Expression Lysate (2)
Primary (41)
Recombinant (5)
Sandwich (2)
CCT2 / CCT Beta (50)
Human (42)
Mouse (28)
Rat (13)
Bat (1)
Bovine (7)
Chimpanzee (6)
Dog (7)
Drosophila (3)
Frog (1)
Gibbon (3)
Guinea pig (6)
Hamster (1)
Horse (7)
Monkey (8)
Non-Human Primate (2)
Orangutan (3)
Pig (7)
Rabbit (6)
Xenopus (1)
Zebrafish (4)
IHC (8)
IHC-P (5)
WB (40)
Flo (3)
ELISA (11)
ICC (2)
IF (11)
IP (4)
Peptide-ELISA (1)
rabbit (27)
mouse (14)
Product Group
IHCPlus (2)
IgG (8)
IgG1 (6)
IgG1,k (6)
IgG2a (2)
monoclonal mc (14)
polyclonal pc (27)
5B5C4 (2)
5B5F5 (2)
F39 P7 F11 (2)
96-Well Strip Plate (2)
APC (1)
APC Conjugated (2)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (23)
aa1-488 (8)
aa257-306 (4)
aa89-138 (4)
aa117-217 (1)
aa325-375 (1)
aa484-534 (1)
No (48)
Yes (2)
Cell Lysates (1)
Tissue Homogenates (2)
6His, N-terminus (1)
GST, N-terminus (1)
His-S (1)
His-SUMO (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Yeast (1)
Purified (1)
CCT2 / CCT Beta Antibody - Anti-CCT2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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CCT2 / CCT Beta Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CCT2 / CCT Beta Antibody - Immunohistochemistry of paraffin-embedded Rat stomach tissue.
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CCT2 / CCT Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CCT2 / CCT Beta Antibody - Anti-CCT2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.
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CCT2 / CCT Beta Mouse anti-Human Monoclonal (F39 P7 F11) Antibody
Xenopus, Zebrafish, Pig, Horse, Rat, Hamster, Mouse, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µg/$460
CCT2 / CCT Beta Antibody - TCP-1 beta Antibody in Immunofluorescence (IF)
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CCT2 / CCT Beta Mouse anti-Human Monoclonal (5B5C4) Antibody
Mouse, Rat, Non-Human Primate, Human
Flo, ICC, IF, WB
Unconjugated
100 µl/$518
CCT2 / CCT Beta Antibody - Immunofluorescence of 3T3-L1 cells using CCT2 mouse monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
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CCT2 / CCT Beta Mouse anti-Human Monoclonal (5B5C4) Antibody
Human
ELISA, Flo, IF, WB
Unconjugated
100 µl/$459
CCT2 / CCT Beta Antibody - Immunofluorescence (IF) analysis of 3T3-L1 cells using TCP-1 beta Monoclonal Antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
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CCT2 / CCT Beta Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human, Monkey
ELISA, Flo, IF, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
CCT2 / CCT Beta Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue at dilution 1:100
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CCT2 / CCT Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$294; 100 µl/$360
CCT2 / CCT Beta Protein - Recombinant  Chaperonin Containing TCP1, Subunit 2 By SDS-PAGE
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E. coli
His-S
56.4 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
CCT2 / CCT Beta Antibody - TCP1 beta was detected in paraffin-embedded sections of mouse gaster tissues using rabbit anti- TCP1 beta Antigen Affinity purified polyclonal antibody
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CCT2 / CCT Beta Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Select
CCT2 / CCT Beta Mouse anti-Human Monoclonal (aa117-217) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$705
Select
CCT2 / CCT Beta Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
Select
CCT2 / CCT Beta Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IF, WB
Biotin Conjugated
100 µl/$904
Select
CCT2 / CCT Beta Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IF, WB
FITC Conjugated
100 µl/$904
Select
CCT2 / CCT Beta Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IF, WB
PE Conjugated
100 µl/$904
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CCT2 / CCT Beta Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IF, WB
APC Conjugated
100 µl/$904
CCT2 / CCT Beta Antibody - Western blot of CCT2 / CCT Beta antibody.
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CCT2 / CCT Beta Rabbit anti-Human Polyclonal (aa1-488) Antibody
Mouse, Human
ICC, IP, WB
Unconjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$597; 2 ml/$826; 5 ml/$1,352
Select
CCT2 / CCT Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CCT2 / CCT Beta Rabbit anti-Human Polyclonal (aa325-375) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
CCT2 / CCT Beta Antibody - Western blot using CCT2 monoclonal antibody against human CCT2 (AA: 87-290) recombinant protein. (Expected MW is 47.9 kDa)
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CCT2 / CCT Beta Mouse anti-Human Monoclonal (5B5F5) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$459
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CCT2 / CCT Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CCT2 / CCT Beta Antibody - Western blot.
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CCT2 / CCT Beta Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
CCT2 / CCT Beta Antibody - IHC testing of FFPE human testis with TCP1 beta antibody at 1ug/ml. HIER: steam in pH6 citrate buffer and allow to cool prior to staining.
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CCT2 / CCT Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
100 µg/$575
CCT2 / CCT Beta Antibody - Left and Center: IHC of normal (left) and cancerous (center) colon tissue using TCP-1 antibody (T-Complex Protein 1,   subunit). Right: Western blot of TCP-1 antibody on Calu6 (1) and HT-29 (2) cell lysates.
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CCT2 / CCT Beta Mouse anti-Frog Monoclonal (F39 P7 F11) Antibody
Frog, Rat, Mouse, Human
IHC, WB
Unconjugated
200 µg/$466
CCT2 / CCT Beta Antibody - Western Blot (WB) analysis using TCP-1 beta Monoclonal Antibody against HeLa (1), MCF-7 (2), Jurkat (3), T47D (4), K562 (5), A431 (6), NIH/3T3 (7), PC-12 (8) and Cos7 (9) cell lysate.
Select
CCT2 / CCT Beta Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
Select
CCT2 / CCT Beta Rabbit anti-Human Polyclonal (aa484-534) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Viewing 1-25 of 50 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).