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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CCR8 Antibody (2nd Extracellular Domain) LS‑C4405
CCR8 antibody LS-C4405 is an unconjugated goat polyclonal antibody to CCR8 from human and monkey. Validated for ELISA, IHC and WB.
Antibody
Catalog
Size
Price
LS-C4405-100
100 µg (1 mg/ml)
$530

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Antibody
Species: Human
Applications: IHC, Western blot, Flow Cytometry, ELISA

Product Description

CCR8 antibody LS-C4405 is an unconjugated goat polyclonal antibody to CCR8 from human and monkey. Validated for ELISA, IHC and WB.
About CCR8
CCR8 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. P51685 NM_005201 NP_005192.1

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Specifications

Target
Human CCR8
Host
Goat
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Predicted
Bovine, Horse (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC (1:300)
  • Western blot (1:2000)
  • ELISA (1:75000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CCR8 antibody was raised against synthetic peptide (CYSFYNQQTLK) corresponding to the 2nd extracellular domain sequence of human CCR8. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Bovine, Horse (91%); Elephant, Panda, Bat (82%).
Epitope
2nd Extracellular Domain
Specificity
Peptide sequence is <50% identical to other Chemokine receptors in this region. Cross-reacts with human.
Usage
ELISA: 1:75000. Western Blot: 1:2000. Immunohistochemistry; 1:300.
Presentation
PBS, pH 7.2, 0.09% Sodium Azide, BSA
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.

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Requested From: United States
Date Requested: 9/20/2018

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