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Anti-CCR6 Antibody (aa18-46) LS-C187844

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $375
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CCR6 Antibodies

Anti-CCR6 Antibody (Extracellular Domain) IHC-plus™ LS-A356
Rabbit Polyclonal to Human CCR6
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-CCR6 Antibody (C-Terminus) IHC-plus™ LS-A358
Rabbit Polyclonal to Human CCR6
Human, Monkey
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-CCR6 Antibody (N-Terminus) LS-C121491
Rabbit Polyclonal (IgG) to Human CCR6
Human, Rat
IHC - Paraffin, Western blot
Unconjugated

100% Guaranteed 100% Guaranteed
Goat Polyclonal (IgG) to Human CCR6
Human, Mouse
IHC - Paraffin, Western blot, ELISA
Unconjugated

Details

Human CCR6
Goat
Human, Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Affinity purified
Unmodified

Applications

  • IHC - Paraffin (1:125)
  • Western blot (1:250)
  • ELISA (1:35000)

Specificity and Use

CCR6 antibody was raised against synthetic peptide YFVSVNTSYYSVDSEMLLCSLQEVRQFSR corresponding to amino acids 18-46 of human CD196. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon (100%); Chimpanzee (97%); Monkey (86%).
aa18-46
Recognizes human CD196, otherwise known as CCR6 (C-C chemokine receptor type 6), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts as a specific receptor for the C-C chemokine LARC (Liver and activation-regulated chemokine)/MIP-3alpha, a selective chemoattractant which induces calcium flux in CD196-expressing lymphocytes. CD196 is preferentially expressed by B cells, memory T cells and immature dendritic cells and plays an important role in B lineage maturation and antigen-driven B cell differentiation. CD196 acts as a co-receptor for HIV1 infection, and is selectively expressed by mucosa-associated non-Hodgkin's lymphoma, making the interaction between CD196 and LARC a potential therapeutic target in these malignancies. Cross-reacts with mouse CD196, where linear epitopes are accessible.

Packaging

PBS, 0.1% sodium azide, 0.1% BSA
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About CCR6

P51684 NM_004367 NP_004358.2

CCR6 Antibody, C-c chemokine receptor 6 Antibody, CD196 antigen Antibody, BN-1 Antibody, C-C chemokine receptor type 6 Antibody, C-C CKR-6 Antibody, Chemokine c-c motif receptor 6 Antibody, CKRL3 Antibody, CMKBR6 Antibody, Chemokine (C-C) receptor 6 Antibody, Chemokine receptor-like 3 Antibody, Cc chemokine receptor 6 Antibody, CC-CKR-6 Antibody, CCR-6 Antibody, DCR2 Antibody, DRY6 Antibody, G protein-coupled receptor 29 Antibody, DRY-6 Antibody, G-protein coupled receptor 29 Antibody, GPR29 Antibody, GPRCY4 Antibody, Strl-22 Antibody, STRL22 Antibody, CD196 Antibody, CKR-L3 Antibody, GPR-CY4 Antibody, LARC receptor Antibody

CCR6 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha).

Immunohistochemistry

Immunohistochemistry
Immunohistochemistry of paraffin-embeddedi mouse spleen stained with Goat anti-Human CD196

Immunohistochemistry

Immunohistochemistry
Immunohistochemistry of paraffin-embeddedi human spleen stained with Goat anti-Human CD196

Requested From: United States
Date Requested: 12/3/2016

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