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CCR6
chemokine (C-C motif) receptor 6
CCR6 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.
| Gene Name: | chemokine (C-C motif) receptor 6 |
| Family/Subfamily: | GPCR , Chemokine |
| Synonyms: | CCR6, C-c chemokine receptor 6, CD196 antigen, BN-1, C-C chemokine receptor type 6, C-C CKR-6, Chemokine c-c motif receptor 6, CKRL3, CMKBR6, Chemokine (C-C) receptor 6, Chemokine receptor-like 3, Cc chemokine receptor 6, CC-CKR-6, CCR-6, DCR2, DRY6, G protein-coupled receptor 29, DRY-6, G-protein coupled receptor 29, GPR29, GPRCY4, Strl-22, STRL22, CD196, CKR-L3, GPR-CY4, LARC receptor |
| Target Sequences: | NM_004367 NP_004358.2 P51684 |
Publications (2)
1
Expression of the chemokine receptor CCR6 correlates with a favorable prognosis in patients with adenocarcinoma of the lung. Minamiya Y, Saito H, Takahashi N, Ito M, Toda H, Ono T, Konno H, Motoyama S, Ogawa J. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2011 32:197-202.
[PubMed:20872189]
Related Antibodies: LS-B2481.
2
Identification of the Single Immunodominant Region of the Native Human CC Chemokine Receptor 6 Recognized by Mouse Monoclonal Antibodies. Dorgham K, Dejou C, Piesse C, Gorochov G, Pène J, Yssel H. PloS one. 2016 11:e0157740. (Flo, Bind; Mouse)
[Full Text Article]
[PubMed:27336468]
[PMC:PMC4919008]
Related Antibodies: LS-A356.
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CCR6 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
CCR6 Goat anti-Human Polyclonal (aa18-46) Antibody
Human
ELISA, Flo, ICC, IHC, IHC-P
Unconjugated
50 µg/$555
Fast Shipping
CCR6 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
CCR6 Rat anti-Mouse Monoclonal (18B9E6) Antibody
Mouse
IHC, IHC-P, WB
Unconjugated
0.1 mg/$386
CCR6 Goat anti-Human Polyclonal (aa18-46) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.1 mg/$500
CCR6 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$564
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
![CCR6 Antibody - Immunohistochemistry-Paraffin: CCR6 Antibody (18B9E6) [Azide Free] - Formalin-fixed, paraffin-embedded normal mouse testis tissue stained with CD196 antibody (5 ug/ml), peroxidase-conjugate and DAB chromogen. Note cytoplasmic and membrane staining. This image was taken for the unmodified form of this product. Other forms have not been tested.](https://lsbio-7d62.kxcdn.com/image2/ccr6-antibody-clone-18b9e6-azide-free-ls-c366534/257380_1943401.jpg)
CCR6 Rat anti-Mouse Monoclonal (Azide-free) (18B9E6) Antibody
Mouse
IHC, IHC-P, WB
Unconjugated, Azide-free
0.1 mg/$386
CCR6 Rabbit anti-Human Polyclonal (aa22-374) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
CCR6 Rabbit anti-Human Polyclonal (aa22-374) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
CCR6 Rabbit anti-Human Polyclonal (aa22-374) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
CCR6 Rabbit anti-Human Polyclonal (aa22-374) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
CCR6 Mouse anti-Human Monoclonal (PE) (G034E3) Antibody
Human
Flo
PE Conjugated
20 Tests/$256; 100 Tests/$346; 200 Tests/$415
CCR6 Goat anti-Human Polyclonal (aa18-46) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µg/$556
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
CCR6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CCR6 Rabbit anti-Human Polyclonal (aa71-87) Antibody
Mouse, Rat, Hamster, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µg/$723
CCR6 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$380
CCR6 Mouse anti-Human Monoclonal (aa1-46) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$586
CCR6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CCR6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CCR6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CCR6 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CCR6 Rat anti-Mouse Monoclonal Antibody
Mouse
WB
Unconjugated
25 µg/$288; 100 µg/$414
CCR6 Rabbit anti-Mouse Polyclonal (Preservative Free) Antibody
Mouse
WB
Unconjugated, Preservative Free
100 µl/$412
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