Human CCR5

Goat

Human (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Affinity purified

Unmodified

Synthetic peptide YQVSSPIYDINYYTSEPCQKINVKQIAA corresponding to amino acids 3-30 within the N-Terminus of human CD195. Percent identity by BLAST analysis: Human (100%); Chimpanzee, Monkey (96%); Orangutan, Baboon (93%).

aa3-30

Recognizes human CD195, also known as C-C chemokine receptor type 5, CCR5 or C-C CKR-5. CD195 is a 353 amino acid ~37 kD multiple pass transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, preferentially expressed by a subset of memory Th1 (type 1 helper T) cells. Binds to an epitope within the N-terminal (NT) region of CD195. CD195 acts as a high-affinity receptor for several chemotactic chemokines, including MIP-1 alpha (macrophage inflammatory protein 1 alpha), MIP-1 beta, and RANTES (regulated on activation normal T expressed and secreted protein). CD195 is also a major co-receptor for HIV-1 infection, with variations in the CD195 gene, influencing the rate of progression into AIDS. Is suitable for use in immunocytochemistry on human peripheral blood leucocytes.

• IHC - Paraffin (1:300)
• IHC - Frozen
• Western blot (1:1000)
• ELISA (1:50000)

PBS, 0.1% Sodium Azide, 0.1% BSA

Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P51681 NCBI: NM_000579 NP_000570.1