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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CCR4 Antibody (aa8‑26) LS‑C83951
Note: This antibody replaces LS-C86015, LS-C12625
Antibody
CCR4 antibody LS-C83951 is an unconjugated goat polyclonal antibody to mouse CCR4. Validated for ELISA, Flow, IHC and WB.
Catalog
Size
Price
LS-C83951-200
200 µg
Unavailable

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Antibody
Species: Mouse
Applications: IHC, IHC - Frozen, Western blot, Flow Cytometry, ELISA

Product Description

CCR4 antibody LS-C83951 is an unconjugated goat polyclonal antibody to mouse CCR4. Validated for ELISA, Flow, IHC and WB.
About CCR4
High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. P51679 NM_005508 NP_005499.1

CCR4 Antibody, C-C chemokine receptor type 4 Antibody, CD194 Antibody, CD194 antigen Antibody, C-C CKR-4 Antibody, Chemr13 Antibody, CKR-4 Antibody, CC chemokine receptor 4 Antibody, CC-CKR-4 Antibody, CCR-4 Antibody, HGCN:14099 Antibody, C-c chemokine receptor 4 Antibody, Chemokine (C-C) receptor 4 Antibody, CKR4 Antibody, CMKBR4 Antibody, K5-5 Antibody


Specifications

Target
Mouse CCR4
Host
Goat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • Western blot
  • Flow Cytometry
  • ELISA (1:25000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CCR4 antibody was raised against synthetic peptide DTTQDETVYNSYYFYESMP-C corresponds to amino acid residues 8 - 26 of mouse CCR4 with cysteine added for coupling to a carrier protein. Percent identity by BLAST analysis: Mouse (100%).
Epitope
aa8-26
Specificity
Peptide sequence is <50 % identical to other human chemokine receptors in this region. The antibody recognizes mouse CCR4 and has no cross-reactivity to human CCR4.
Presentation
Phosphate buffered saline, 1 mg/ml BSA, 0.1% sodium azide
Storage
Short term: -20°C; Long term: -70°C; Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/24/2018

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