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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CCR3 Antibody (aa5‑28) IHC‑plus™ LS‑B8238
Note: This antibody replaces LS-C83983
CCR3 antibody LS-B8238 is an unconjugated goat polyclonal antibody to CCR3 from human and mouse. Validated for ICC, IHC and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B8238-50
50 µg (1 mg/ml)
Unavailable

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Product Description

CCR3 antibody LS-B8238 is an unconjugated goat polyclonal antibody to CCR3 from human and mouse. Validated for ICC, IHC and WB. Tested on 20 paraffin-embedded human tissues.
About CCR3
CCR3 is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. P51677 NM_001837 NP_001828.1

CCR3 Antibody, C-C chemokine receptor type 3 Antibody, B-chemokine receptor Antibody, CD193 Antibody, CD193 antigen Antibody, Chemokine c-c motif receptor 3 Antibody, C-C chemokine receptor 3 Antibody, CKR3 Antibody, CC-CKR-3 Antibody, CCR-3 Antibody, CMKBR3 Antibody, Eosinophil eotaxin receptor Antibody, Eotaxin receptor Antibody, C-C CKR-3 Antibody, CC chemokine receptor 3 Antibody


Specifications

Target
Mouse CCR3
Host
Goat
Reactivity
Mouse, Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • ICC (1:200)
  • Western blot (1:500)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CCR3 antibody was raised against synthetic peptide TDEIKTVVESFETTPYEYEWAPPC corresponding to aa 5-28 of the N-terminal domain of mouse CCR3. Percent identity by BLAST analysis: Mouse (100%); Rat, Hamster (83%).
Epitope
aa5-28
Specificity
This antibody recognizes mouse CCR3 and the peptide sequence is <50 % identical to other chemokine receptors in this region.
Presentation
10 mM KHPO4, 140 mM NaCl with 0.1% sodium azide and 1 mg/ml BSA
Storage
Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Immunohistochemistry

Anti-CCR3 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8238 dilution 5 ug/ml.
Anti-CCR3 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8238 dilution 5 ug/ml.

Immunohistochemistry

Anti-CCR3 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8238 dilution 5 ug/ml.
Anti-CCR3 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8238 dilution 5 ug/ml.

Immunohistochemistry

Anti-CCR3 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8238 dilution 5 ug/ml.
Anti-CCR3 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8238 dilution 5 ug/ml.

Immunohistochemistry

Anti-CCR3 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8238 dilution 5 ug/ml.
Anti-CCR3 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8238 dilution 5 ug/ml.


Requested From: 
Date Requested: 6/22/2018

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