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Anti-CCR2 Antibody (aa20-100, Biotin) LS-C143449

Catalog	Size	Price
LS-C143449-100	100 µl (1 mg/ml)	Unavailable

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Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

Antibody:	Rabbit Polyclonal (IgG) to Mouse CCR2
Reactivity:	Mouse, Human
Application:	ICC, Western blot, Flow Cytometry (applications tested for the base form of this product only)
Format:	Biotin Conjugated

CCR2 Antibody - Immunocytochemical analysis of CCR2 in NIH/3T3 cells. This image was taken for the unconjugated form of this product. Other forms have not been tested.

CCR2 Antibody - FACS analysis of CCR2 in NIH/3T3 cells. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Details

Target:	Mouse CCR2
Host:	Rabbit
Reactivity:	Mouse, Human (tested or 100% immunogen sequence identity)
Clonality:	IgG Polyclonal
Conjugations:	Biotin. Also available Unconjugated or conjugated with DY650, DY488, DY550.
Purification:	Affinity purified
Modifications:	Unmodified

Applications

Approved:

ICC (1:50)
Western blot (1 µg/ml)
Flow Cytometry
(applications tested for the base form of this product only)

Specificity and Use

Immunogen:	CCR2 antibody was raised against synthetic peptide made to an N-terminal portion of the mouse CCR2 protein (within residues 20-100). [Swiss-Prot# P51683]
Epitope:	aa20-100
Usage:	The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

Presentation:	PBS, 0.05% sodium azide
Storage:	Store at 4°C in the dark.
Restrictions:	For research use only.

About CCR2

Uniprot: P41597 NCBI: NP_001116868.1

Synonyms: CCR2 Antibody, C-C chemokine receptor type 2 Antibody, CD192 Antibody, Cc chemokine receptor 2 Antibody, CCR-2 Antibody, CCR2A Antibody, C-C CKR-2 Antibody, CKR2 Antibody, CD192 antigen Antibody, CKR2A Antibody, CKR2B Antibody, Mcp1 receptor Antibody, MCP-1 receptor Antibody, MCP-1-R Antibody, C-c chemokine receptor 2 Antibody, CC-CKR-2 Antibody, Cc-ckr2 Antibody, CCR2B Antibody, CMKBR2 Antibody, Mcp1r Antibody

Description: CCR2, a Chemokine Receptor, is a regulator of monocyte/macrophage trafficking and is upregulated in response to inflammation. Resistance to HIV-1 infection or delayed progression to AIDS may be linked to CCR2 polymorphisms. The ligand for CCR2 is monocyte chemoattractant protein (MCP-1), a chemokine produced by endothelial cells, smooth muscle cells, and macrophages.

(More About CCR2)

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Immunocytochemistry

CCR2 Antibody - Immunocytochemical analysis of CCR2 in NIH/3T3 cells. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Flow Cytometry

CCR2 Antibody - FACS analysis of CCR2 in NIH/3T3 cells. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From:
Date Requested: 4/22/2018

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