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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CCR10 / GPR2 Antibody (aa9‑31) LS‑C187843
GPR2 antibody LS-C187843 is an unconjugated goat polyclonal antibody to human GPR2 (CCR10). Validated for ELISA, Flow, IHC and WB.
Catalog
Size
Price
LS-C187843-100
100 µg (1 mg/ml)
Unavailable

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Product Description

GPR2 antibody LS-C187843 is an unconjugated goat polyclonal antibody to human GPR2 (CCR10). Validated for ELISA, Flow, IHC and WB.
About CCR10 / GPR2
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. P46092 NM_016602 NP_057686.2

CCR10 Antibody, C-C CKR-10 Antibody, CC-CKR-10 Antibody, CCR-10 Antibody, C-C chemokine receptor type 10 Antibody, CC chemokine receptor 10 Antibody, G-protein coupled receptor 2 Antibody, GPR2 Antibody, G protein-coupled receptor 2 Antibody


Specifications

Target
Human CCR10 / GPR2
Host
Goat
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:125)
  • Western blot (1:30000)
  • Flow Cytometry (1:1)
  • ELISA (1:50000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CCR10 / GPR2 antibody was raised against synthetic peptide VSWGHYSGDEEDAYSAEPLPELC corresponding to amino acids 9-31 of human CCR10. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan (100%); Gibbon, Monkey (96%); Marmoset, Rabbit, Pig (87%); Galago, Rat, Ferret (83%).
Epitope
aa9-31
Specificity
Recognizes human CCR10 (C-C chemokine receptor type 10), otherwise known as GPR2, (G-protein coupled receptor 2), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, expressed by melanocytes, dermal fibroblasts, and dermal microvascular endothelial cells, which acts as a receptor for the skin-associated chemokine CCL27 (SCYA27/CTACK), and is implicated in T cell-mediated skin inflammation and possibly skin homeostasis.
Presentation
PBS, 0.1% sodium azide, 0.1% BSA
Storage
4°C or -20°C, Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Immunohistochemistry of paraffin-embeddedi human tonsil stained with Goat anti-Human CCR10
Immunohistochemistry of paraffin-embeddedi human tonsil stained with Goat anti-Human CCR10

Immunohistochemistry

Immunohistochemistry of paraffin-embeddedi human spleen stained with Goat anti-Human CCR10
Immunohistochemistry of paraffin-embeddedi human spleen stained with Goat anti-Human CCR10

Immunohistochemistry

Immunohistochemistry of paraffin-embeddedi human tonsil stained with Goat anti-Human CCR10
Immunohistochemistry of paraffin-embeddedi human tonsil stained with Goat anti-Human CCR10

Immunohistochemistry

Immunohistochemistry of paraffin-embeddedi human spleen stained with Goat anti-Human CCR10
Immunohistochemistry of paraffin-embeddedi human spleen stained with Goat anti-Human CCR10

Immunohistochemistry

Immunohistochemistry of paraffin-embeddedi human tonsil stained with Goat anti-Human CCR10
Immunohistochemistry of paraffin-embeddedi human tonsil stained with Goat anti-Human CCR10

Immunohistochemistry

Immunohistochemistry of paraffin-embeddedi human spleen stained with Goat anti-Human CCR10
Immunohistochemistry of paraffin-embeddedi human spleen stained with Goat anti-Human CCR10

Immunohistochemistry

Immunohistochemistry of paraffin-embeddedi human tonsil stained with Goat anti-Human CCR10
Immunohistochemistry of paraffin-embeddedi human tonsil stained with Goat anti-Human CCR10

Immunohistochemistry

Immunohistochemistry of paraffin-embeddedi human spleen stained with Goat anti-Human CCR10
Immunohistochemistry of paraffin-embeddedi human spleen stained with Goat anti-Human CCR10


Requested From: 
Date Requested: 6/21/2018

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