Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

CCNH / Cyclin H

cyclin H

CCNH / Cyclin H belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.

Gene Name: cyclin H
Synonyms: CCNH, Cyclin H, p34, p37, CAK, CAK complex subunit, Cyclin-H, MO15-associated protein
Target Sequences: NM_001239 NP_001230.1 P51946

Publications (3)

1
Cyclins B1, T1, and H differ in their molecular mode of interaction with cytomegalovirus protein kinase pUL97. Steingruber M, Keller L, Socher E, Ferre S, Hesse AM, Couté Y, Hahn F, Büscher N, Plachter B, Sticht H, Marschall M. The Journal of biological chemistry. 2019 April;294:6188-6203. [Full Text Article] [PubMed:30782840] [PMC:PMC6463711] Related Antibodies: LS-C331195.
2
Functional Relevance of the Interaction between Human Cyclins and the Cytomegalovirus-Encoded CDK-Like Protein Kinase pUL97. Martin Schütz, Mirjam Steingruber, Eileen Socher , Regina Müller, Sabrina Wagner, Merle Kögel, Heinrich Sticht, Manfred Marschall. Viruses. 2021 Jun;13:1248. [Full Text Article] [PubMed:34198986] [PMC:PMC8310212] Related Antibodies: LS-C331195.
3
Highly Conserved Interaction Profiles between Clinically Relevant Mutants of the Cytomegalovirus CDK-like Kinase pUL97 and Human Cyclins: Functional Significance of Cyclin H. Martin Schütz, Regina Müller, Eileen Socher, Christina Wangen, Florian Full, Emanuel Wyler, Diana Wong, Myriam Scherer, Thomas Stamminger, Sunwen Chou, William D Rawlinson, Stuart T Hamilton, Heinrich Sticht, Manfred Marschall. International journal of molecular sciences. 2022 October;23: [Full Text Article] [PubMed:36233116] [PMC:PMC9569496] Related Antibodies: LS-C331195.

☰ Filters
Antibodies (52)
Proteins (8)
ELISA Kits (2)
Cell-Based (1)
Cell-Based Phosphorylation (1)
Over-Expression Lysate (2)
Primary (52)
Recombinant (6)
CCNH / Cyclin H (62)
Human (54)
Mouse (31)
Rat (24)
Bat (9)
Bovine (9)
Chimpanzee (9)
Dog (5)
Gibbon (9)
Guinea pig (9)
Hamster (3)
Horse (6)
Monkey (11)
Orangutan (6)
Pig (13)
Rabbit (9)
IHC (21)
IHC-P (9)
WB (49)
Flo (9)
ELISA (16)
ICC (2)
IF (14)
IP (4)
Peptide-ELISA (5)
rabbit (43)
mouse (9)
Product Group
IHCPlus (2)
IgG (31)
IgG1 (1)
IgG2a (1)
IgG2a,k (1)
IgG2b (1)
IgG2b,k (1)
monoclonal mc (8)
polyclonal pc (44)
1B8 (1)
AT3G6 (1)
96-Well Microplate (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (1)
Unconjugated (35)
C-Terminus (10)
aa269-299 (7)
aa50-99 (4)
pThr315 (4)
250-330 aa (2)
Glu311 (1)
aa24-52 (1)
aa262-311 (1)
aa274-323 (1)
p315 (1)
No (61)
Yes (1)
Adherent Cell Cultures (2)
6His, N-terminus (2)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (7)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (3)
Low endotoxin level (2)
CCNH / Cyclin H Antibody - Immunofluorescence analysis of HeLa cells.
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal Antibody
Human
IF, IP, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CCNH / Cyclin H Antibody - Anti-CCNH / Cyclin H antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
CCNH / Cyclin H Mouse anti-Human Monoclonal (1B8) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CCNH / Cyclin H Antibody - Immunohistochemical analysis of Cyclin H staining in human kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Pig, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, IP, WB
Unconjugated
100 µg/$331
CCNH / Cyclin H Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal (aa262-311) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
CCNH / Cyclin H Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Cyclin H (Ab-315) antibody.
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal (p315) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
CCNH / Cyclin H Antibody - Western blot of HeLa cell lysate using Cyclin H Antibody
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
CCNH / Cyclin H Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Cyclin H Antibody. The picture on the right is blocked with the synthesized peptide.
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal (aa274-323) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CCNH / Cyclin H Antibody - 1:100 staining mouse brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal (pThr315) Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CCNH / Cyclin H Antibody - Western blot of Cyclin H antibody
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal (250-330 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CCNH / Cyclin H Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CCNH / Cyclin H Antibody - Immunohistochemistry image of paraffin-embedded human adrenal gland tissue at a dilution of 1:100
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal (pThr315) Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
CCNH / Cyclin H Antibody - Western blot of Cyclin H (E311) pAb in extracts from K562 cells.
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal (Glu311) Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal (250-330 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal (aa269-299) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal (aa269-299) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal (aa269-299) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal (aa269-299) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal (aa269-299) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal (aa269-299) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
CCNH / Cyclin H Antibody - CCNH / Cyclin H antibody AVARP03026_T100-NP_001230-CCNH (cyclin H) Antibody IHC of formalin-fixed, paraffin-embedded human Lung. Positive label: Epithelial cells of bronchiole indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
CCNH / Cyclin H Antibody - Immunohistochemical analysis of Cyclin H (pT315) staining in human kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
CCNH / Cyclin H Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Pig, Human, Monkey
IHC, IHC-P, WB
Unconjugated
30 µl/$263; 100 µl/$315; 200 µl/$379
Select
CCNH / Cyclin H Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
150 µg/$842
Viewing 1-25 of 62 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).