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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CCNE1 / Cyclin E1 Antibody (phospho‑Thr395) LS‑C123355
Antibody
Cyclin E1 antibody LS-C123355 is an unconjugated rabbit polyclonal antibody to Cyclin E1 (CCNE1) from human and monkey. Validated for IHC.
Catalog
Size
Price
LS-C123355-50
50 µg
Unavailable

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Product Description

Cyclin E1 antibody LS-C123355 is an unconjugated rabbit polyclonal antibody to Cyclin E1 (CCNE1) from human and monkey. Validated for IHC.
About CCNE1 / Cyclin E1
CCNE1 / Cyclin E1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. P24864 NM_001238 NP_001229.1

CCNE1 Antibody, Cyclin E1 Antibody, CCNE Antibody, Cyclin Es Antibody, Cyclin Et Antibody, G1/S-specific cyclin-E1 Antibody, G1/s-specific cyclin e Antibody, Cyclin E Antibody


Specifications

Target
Human CCNE1 / Cyclin E1
Host
Rabbit
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC (1:50 - 1:100)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic phosphopeptide corresponding to human Cyclin E1 around the phosphorylation site of threonine395 (L-L-TP-P-P).
Epitope
pThr395
Specificity
Recognizes human Cyclin E1 when phosphorylated at Thr395.
Usage
Suitable for use in Immunohistochemistry:1:50-100.
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Storage
May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/24/2018

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