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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CCND3 / Cyclin D3 Antibody (Gly277) LS‑C175891
Cyclin D3 antibody LS-C175891 is an unconjugated rabbit polyclonal antibody to human Cyclin D3 (CCND3). Validated for WB.
Catalog
Size
Price
LS-C175891-100
100 µl
Unavailable

Popular CCND3 / Cyclin D3 Products

Formalin-fixed, paraffin-embedded human tonsil stained with peroxidase-conjugate and AEC chromogen. Note nuclear staining of cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry
Formalin-fixed, paraffin-embedded human tonsil stained with peroxidase-conjugate and AEC chromogen. Note nuclear staining of cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry
Immunohistochemistry Image
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Antibody
Species: Human
Applications: Western blot, Immunoprecipitation
Antibody
Species: Human, Monkey, Mouse, Rat
Applications: IHC, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry, Neutralization

Product Description

Cyclin D3 antibody LS-C175891 is an unconjugated rabbit polyclonal antibody to human Cyclin D3 (CCND3). Validated for WB.
About CCND3 / Cyclin D3
Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. P30281 NM_001760 NP_001751.1

CCND3 Antibody, D3-type cyclin Antibody, G1/S-specific cyclin D3 Antibody, G1/S-specific cyclin-D3 Antibody, Cyclin D3 Antibody


Specifications

Target
Human CCND3 / Cyclin D3
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
Immunogen
Synthetic peptide around Gly277 of human Cyclin D3
Epitope
Gly277
Specificity
Human Cyclin D3
Presentation
PBS, pH 7.2, 15 mM sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Customer Reviews (0)


Images


Western blot

Western blot of Cyclin D3 (G277) pAb in extracts from HeLa cells.
Western blot of Cyclin D3 (G277) pAb in extracts from HeLa cells.

Western blot

Western blot of Cyclin D3 (G277) pAb in extracts from HeLa cells.
Western blot of Cyclin D3 (G277) pAb in extracts from HeLa cells.

Western blot

Western blot of Cyclin D3 (G277) pAb in extracts from HeLa cells.
Western blot of Cyclin D3 (G277) pAb in extracts from HeLa cells.

Western blot

Western blot of Cyclin D3 (G277) pAb in extracts from HeLa cells.
Western blot of Cyclin D3 (G277) pAb in extracts from HeLa cells.


Requested From: 
Date Requested: 6/20/2018

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