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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CCND1 / Cyclin D1 Antibody (N‑Terminus) LS‑C172072
Cyclin D1 antibody LS-C172072 is an unconjugated rabbit polyclonal antibody to Cyclin D1 (CCND1) from human, mouse and rat. Validated for WB.
Catalog
Size
Price
LS-C172072-100
100 µg
Unavailable

Popular CCND1 / Cyclin D1 Products

Antibody
Species: Human, Monkey, Mouse, Rat, Dog
Applications: Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry, Blocking
Antibody
Species: Human, Mouse, Rat
Applications: Functional Assay
Anti-CCND1 / Cyclin D1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3452 concentration 10 ug/ml.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Anti-CCND1 / Cyclin D1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4507 concentration 10 ug/ml.
Species: Human, Rat
Applications: IHC, IHC - Paraffin, IHC - Frozen, ICC, Western blot, Immunoprecipitation, Flow Cytometry, ELISA
WB of CCND1 / Cyclin D1 antibody. All lanes: Anti-CCND1 at 0.5ug/ml. Lane 1: Rat Testis Tissue Lysate at 40ug. Lane 2: Rat Ovary Tissue Lysate at 40ug. Lane 3: Rat Brain Tissue Lysate at 40ug. Lane 4: HELA Whole Cell Lysate at 40ug. Lane 5: MM231 Whole Cell Lysate at 40ug. Lane 6: SW620 Whole Cell Lysate at 40ug. Predicted bind size: 33KD. Observed bind size: 33KD.
Species: Human, Mouse, Rat
Applications: Western blot

Product Description

Cyclin D1 antibody LS-C172072 is an unconjugated rabbit polyclonal antibody to Cyclin D1 (CCND1) from human, mouse and rat. Validated for WB.
About CCND1 / Cyclin D1
Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. P24385 NM_053056 NP_444284.1

CCND1 Antibody, B-cell lymphoma 1 protein Antibody, BCL-1 oncogene Antibody, B-cell CLL/lymphoma 1 Antibody, BCL-1 Antibody, Cyclin D1 Antibody, G1/S-specific cyclin-D1 Antibody, U21B31 Antibody, PRAD1 Antibody, BCL1 Antibody, D11S287E Antibody, PRAD1 oncogene Antibody


Specifications

Target
Human CCND1 / Cyclin D1
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Magnetic beads, Sepharose.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
Synthetic peptide corresponding to a sequence at the N-terminal of human Cyclin D1, different to the related mouse sequence by two amino acids.
Epitope
N-Terminus
Specificity
Human, rat, mouse. No cross reactivity with other proteins.
Presentation
5 mg BSA, 0.9 mg sodium chloride, 0.2 mg sodium phosphate, 0.05 mg Thimerosal, 0.05 mg sodium azide
Storage
Short term: 4°C; Long term: -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

 This image was taken for the unconjugated form of this product. Other forms have not been tested.
This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

 This image was taken for the unconjugated form of this product. Other forms have not been tested.
This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

 This image was taken for the unconjugated form of this product. Other forms have not been tested.
This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

 This image was taken for the unconjugated form of this product. Other forms have not been tested.
This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/22/2018

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