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| Catalog Number | Size | Price |
|---|---|---|
| LS-C389432-7 | 7 ml | $574 |
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Monoclonal Mouse anti‑Human CCND1 / Cyclin D1 Antibody (clone DCS‑6, Ready‑to‑Use, IHC, IF, WB) LS‑C389432
Monoclonal Mouse anti‑Human CCND1 / Cyclin D1 Antibody (clone DCS‑6, Ready‑to‑Use, IHC, IF, WB) LS‑C389432
Antibody:
CCND1 / Cyclin D1 Mouse anti-Human Monoclonal (Ready-to-Use) (DCS-6) Antibody
Application:
IHC, IHC-P, IF, WB, Flo
Reactivity:
Human, Monkey, Mouse, Rat
Format:
Unconjugated, Ready-to-Use
Other formats:
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
CCND1 / Cyclin D1 Mouse anti-Human Monoclonal (Ready-to-Use) (DCS-6) Antibody
Application:
IHC, IHC-P, IF, WB, Flo
Reactivity:
Human, Monkey, Mouse, Rat
Format:
Unconjugated, Ready-to-Use
Other formats:
Specifications
Description
Cyclin D1 antibody LS-C389432 is an unconjugated mouse monoclonal antibody to Cyclin D1 (CCND1) from human. It is reactive with human, mouse, rat and other species. Validated for Flow, IF, IHC and WB.
Target
Human CCND1 / Cyclin D1
Synonyms
CCND1 | B-cell lymphoma 1 protein | BCL-1 oncogene | B-cell CLL/lymphoma 1 | BCL-1 | Cyclin D1 | G1/S-specific cyclin-D1 | U21B31 | PRAD1 | BCL1 | D11S287E | PRAD1 oncogene
Host
Mouse
Reactivity
Human, Monkey, Mouse, Rat
(tested or 100% immunogen sequence identity)
Clonality
IgG2a,k
Monoclonal
Clone
DCS-6
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Ready-to-Use.
Also available Unmodified or Azide-free, BSA-free.
Immunogen
Human recombinant full length protein.
Specificity
Human CCND1 / Cyclin D1
Applications
- IHC
- IHC - Paraffin (1:1)
- Immunofluorescence
- Western blot
- Flow Cytometry
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. This antibody recognizes a protein of 36kDa, identified as Cyclin D1. It is a putative proto-oncogene overexpressed in a wide variety of human neoplasms and a key cell cycle regulator. This antibody neutralizes the activity of Cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t (11. 14) (q13. q32) translocation resulting in over-expression. Cyclin D1 antibody is useful in identifying mantle cell lymphomas, which stain positive, from CLL/SLL and follicular lymphomas, which stain negative. Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1. ELISA: Order BSA and Azide-free format for coating.
Presentation
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CCND1 / Cyclin D1
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human, Mouse, Rat
Applications:
Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, IHC - Frozen, ICC, Western blot
Species:
Human
Applications:
Western blot, Immunoprecipitation, ELISA
Species:
Human, Mouse, Rat
Applications:
Immunoprecipitation
Species:
Human, Monkey, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/18/2024
Date Requested: 4/18/2024
