CCN4 / WISP1

WNT1 inducible signaling pathway protein 1

CCN4 / WISP1 is a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. It is 83% identical to the mouse protein at the amino acid level. Multiple alternatively spliced transcript variants have been identified.

☰ Filters

Products

Antibodies (46)

ELISA Kits (19)

Proteins (11)

Type

Custom (1)

Over-Expression Lysate (4)

Primary (46)

Recombinant (7)

Sandwich (16)

Sandwich CLIA (2)

Target

CCN4 / WISP1 (76)

Reactivity

Human (39)

Mouse (26)

Rat (7)

Chimpanzee (3)

Horse (2)

Monkey (2)

Pig (3)

Rabbit (1)

Application

IHC (11)

IHC-Fr (1)

IHC-P (2)

WB (42)

ELISA (13)

ICC (1)

IF (1)

IP (1)

Peptide-ELISA (2)

Host

rabbit (44)

mouse (1)

goat (1)

Isotype

IgG (13)

IgG2a (1)

Clonality

monoclonal mc (1)

polyclonal pc (45)

Format

96-Well Microplate (3)

96-Well Strip Plate (15)

APC (3)

APC Conjugated (4)

Azide-free (1)

Biotin Conjugated (6)

Cy3 Conjugated (3)

Cy7 Conjugated (3)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (4)

Unconjugated (14)

more less

Epitope

aa216-347 (16)

aa213-350 (8)

aa171-200 (7)

aa160-209 (4)

aa354-367 (1)

aa357-367 (1)

Publications

No (76)

Sample Type

Cell Culture Supernatants (7)

Cell Lysates (1)

EDTA Plasma (1)

Heparin Plasma (1)

Plasma (17)

Serum (18)

Tissue Homogenates (9)

Tag

GST (1)

His (2)

His-T7 (1)

Myc-DDK (Flag) (5)

Species

Human (7)

Mouse (2)

Source

293T Cells (2)

E. coli (5)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (2)

Biologically Active

Biologically active (2)

Select

CCN4 / WISP1 Antibody LS-C500015

Antibody:

CCN4 / WISP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

CCN4 / WISP1 Antibody (aa357-367) LS-C55692

Antibody:

CCN4 / WISP1 Goat anti-Human Polyclonal (aa357-367) Antibody

Reactivity:

Horse, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

Select

CCN4 / WISP1 Antibody (aa216-347) LS-C297019

Antibody:

CCN4 / WISP1 Rabbit anti-Human Polyclonal (aa216-347) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

Select

CCN4 / WISP1 Antibody (aa354-367) LS-C313208

Antibody:

CCN4 / WISP1 Rabbit anti-Human Polyclonal (aa354-367) Antibody

Reactivity:

Rabbit, Horse, Human, Monkey

Applications:

ICC, IHC, IHC-Fr, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

Human CCN4 / WISP1 Protein (Recombinant) - LS-G137593

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein.

Molecular Weight:

The 345 amino acids recombinant protein has a predicted molecular mass of 38.1 kD. The predicted N-terminal amino acid is Thr.

Price:

20 µg/$352

Select

CCN4 / WISP1 Antibody LS-C144272

Antibody:

CCN4 / WISP1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

500 µg/$1,089

Select

CCN4 / WISP1 Antibody LS-C661618

Antibody:

CCN4 / WISP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

Human CCN4 / WISP1 (Sandwich ELISA) ELISA Kit - LS-F38167

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

CCN4 / WISP1 Antibody (aa171-200) LS-C330734

Antibody:

CCN4 / WISP1 Rabbit anti-Human Polyclonal (aa171-200) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

CCN4 / WISP1 Antibody (aa171-200, Biotin) LS-C246383

Antibody:

CCN4 / WISP1 Rabbit anti-Human Polyclonal (aa171-200) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

CCN4 / WISP1 Antibody (aa171-200, FITC) LS-C246384

Antibody:

CCN4 / WISP1 Rabbit anti-Human Polyclonal (aa171-200) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

CCN4 / WISP1 Antibody (aa171-200, APC) LS-C246381

Antibody:

CCN4 / WISP1 Rabbit anti-Human Polyclonal (aa171-200) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

CCN4 / WISP1 Antibody (aa171-200, PE) LS-C246385

Antibody:

CCN4 / WISP1 Rabbit anti-Human Polyclonal (aa171-200) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

CCN4 / WISP1 Antibody (aa171-200, Azide-free, HRP) LS-C247973

Antibody:

CCN4 / WISP1 Rabbit anti-Human Polyclonal (aa171-200) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

CCN4 / WISP1 Antibody (aa171-200) LS-C100502

Antibody:

CCN4 / WISP1 Rabbit anti-Human Polyclonal (aa171-200) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

CCN4 / WISP1 Antibody LS-C808897

Antibody:

CCN4 / WISP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

CCN4 / WISP1 Antibody LS-C779839

Antibody:

CCN4 / WISP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

CCN4 / WISP1 Antibody (aa213-350) LS-C297022

Antibody:

CCN4 / WISP1 Rabbit anti-Mouse Polyclonal (aa213-350) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

Select

CCN4 / WISP1 Antibody (aa213-350, Biotin) LS-C298581

Antibody:

CCN4 / WISP1 Rabbit anti-Mouse Polyclonal (aa213-350) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

Select

CCN4 / WISP1 Antibody (aa213-350, APC, Cy7) LS-C736725

Antibody:

CCN4 / WISP1 Rabbit anti-Mouse Polyclonal (aa213-350) (APC, Cy7) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781

• Unconjugated
• Biotin
• APC, Cy7

• Unconjugated
• Biotin
• APC, Cy7

Select

CCN4 / WISP1 Antibody (aa216-347) LS-C373528

Antibody:

CCN4 / WISP1 Rabbit anti-Mouse Polyclonal (aa216-347) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

Select

CCN4 / WISP1 Antibody (aa216-347, Biotin) LS-C424322

Antibody:

CCN4 / WISP1 Rabbit anti-Mouse Polyclonal (aa216-347) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

Select

CCN4 / WISP1 Antibody (aa216-347, FITC) LS-C424324

Antibody:

CCN4 / WISP1 Rabbit anti-Mouse Polyclonal (aa216-347) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765

• Unconjugated
• Biotin
• FITC

• Unconjugated
• Biotin
• FITC

Select

CCN4 / WISP1 Antibody LS-C332504

Antibody:

CCN4 / WISP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

CCN4 / WISP1 Antibody (aa160-209) LS-C151569

Antibody:

CCN4 / WISP1 Rabbit anti-Human Polyclonal (aa160-209) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Viewing 1-25 of 76 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.