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Anti-CCM2 / Malcavernin Antibody (clone 5H4) LS-C173267

Catalog Size Price
LS-C173267-100 100 µl (0.78 mg/ml) Unavailable

Most Popular CCM2 / Malcavernin Antibodies

Anti-CCM2 / Malcavernin Antibody (clone 2E4) LS-C173242
Mouse Monoclonal [clone 2E4] (IgG1) to Human CCM2 / Malcavernin
Human
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
IHC of paraffin-embedded Human Kidney tissue using anti-CCM2 mouse monoclonal antibody.
Anti-CCM2 / Malcavernin Antibody (clone 2F9) LS-C337467
Mouse Monoclonal [clone 2F9] (IgG1) to Human CCM2 / Malcavernin
Human
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-CCM2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Anti-CCM2 / Malcavernin Antibody (clone 1E9) LS-C337468
Mouse Monoclonal [clone 1E9] (IgG1) to Human CCM2 / Malcavernin
Human
IHC, IHC - Paraffin, Western blot
Unconjugated
IHC of paraffin-embedded Human lymph node tissue using anti-CCM2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Anti-CCM2 / Malcavernin Antibody LS-C408980
Rabbit Polyclonal (IgG) to Human CCM2 / Malcavernin
Human, Mouse, Rat
IHC, Western blot
Unconjugated
Immunohistochemistry of paraffin-embedded mouse heart.
Anti-CCM2 / Malcavernin Antibody LS-C482638
Rabbit Polyclonal to Human CCM2 / Malcavernin
Human, Mouse, Rat
IHC, IHC - Paraffin, Western blot
Unconjugated
Immunohistochemical analysis of Malcavernin staining in rat heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.

100% Guaranteed
Mouse Monoclonal [clone 5H4] (IgG2b) to Human CCM2 / Malcavernin
Human
Immunofluorescence, Western blot
Unconjugated

Details

Human CCM2 / Malcavernin
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [5H4]
Unconjugated
Protein A/G purified
Unmodified

Applications

  • Immunofluorescence (1:100)
  • Western blot (1:2000)

Specificity and Use

Full length human recombinant protein of human CCM2(NP_113631) produced in HEK293T cell.
Human CCM2 / Malcavernin

Packaging

PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About CCM2 / Malcavernin

Q9BSQ5 NM_031443 NP_113631.1

CCM2 Antibody, C7orf22 Antibody, Malcavernin Antibody, PP10187 Antibody

Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock.

Immunofluorescence

Anti-CCM2 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CCM2.
Anti-CCM2 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CCM2.

Western blot

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CCM2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CCM2.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CCM2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CCM2.

Requested From: 
Date Requested: 5/25/2018

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