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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CCL8 / MCP2 Antibody (Biotin) LS‑C187696
Antibody
MCP2 antibody LS-C187696 is a biotin-conjugated rabbit polyclonal antibody to mouse MCP2 (CCL8). Validated for ELISA and WB.
Catalog
Size
Price
LS-C187696-50
50 µg (0.1 mg/ml)
Unavailable

Popular CCL8 / MCP2 Products

Western Blot (reducing) of MCP-2 / CCL8 antibody LS-C104673.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Antibody
Species: Mouse
Applications: IHC, IHC - Paraffin, ELISA

Product Description

MCP2 antibody LS-C187696 is a biotin-conjugated rabbit polyclonal antibody to mouse MCP2 (CCL8). Validated for ELISA and WB.
About CCL8 / MCP2
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. P80075 NM_005623 NP_005614.2

CCL8 Antibody, C-C motif chemokine 8 Antibody, HC14 Antibody, MCP2 Antibody, Monocyte chemotactic protein 2 Antibody, Scya10 Antibody, SCYA8 Antibody, Small-inducible cytokine A8 Antibody, MCP-2 Antibody, Chemokine (C-C motif) ligand 8 Antibody


Specifications

Target
Mouse CCL8 / MCP2
Host
Rabbit
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Biotin
Purification
Affinity purified
Modifications
Unmodified
Applications
  • Western blot (0.1 - 0.2 µg/ml)
  • ELISA (0.25 - 1 µg/ml)
Immunogen
CCL8 / MCP2 antibody was raised against recombinant mouse MCP-2.
Specificity
Recognizes mouse MCP-2 (Monocyte Chemoattractant Protein 2), otherwise known as CCL8, a CC chemokine originally isolated from the human osteosarcoma cell line MG-63, which is expressed at highest levels in peripheral blood cells and the small intestine. MCP-2 acts as a chemoattractant for monocytes, lymphocytes, eosinophils and basophils, and signals through binding to the common MCP receptor, chemokine (C-C motif) receptor 2 (CCR2), and also CCR1 and CCR3. Proteolytic cleavage of MCP-2 into the NH2-terminally truncated form, MCP-2 (6-76), results in the loss of chemotactic activity, forming a functional CC chemokine inhibitor, which may be important during inflammatory responses.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS
Reconstitution
500 µl Sterile PBS
Storage
Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/22/2018

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