Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Protein A purified
Specificity and Use
CCL7 / MCP3 antibody was raised against recombinant human MCP-3.
Suitable for use in Neutralization and ELISA. Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of hMCP-3 (100 ng/ml), a concentration of 1-3 ug/ml of this antibody is required. ELISA: 1:20000 dilution of a 1 mg/ml antibody solution will give satisfactory results in a direct ELISA using alkaline phosphatase goat anti-mouse Ig.
PBS, pH 7.2. No preservative added.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
CCL7 / MCP3 is monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q.