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CCL3 / MIP-1-Alpha
chemokine (C-C motif) ligand 3
Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
| Gene Name: | chemokine (C-C motif) ligand 3 |
| Family/Subfamily: | Intercrine , Intercrine beta |
| Synonyms: | CCL3, C-C motif chemokine 3, G0S19-1, Mip1alpha, SCYA3, SIS-beta, Chemokine (C-C motif) ligand 3, LD78ALPHA, MIP-1-alpha, MIP1A, PAT 464.1, Small-inducible cytokine A3 |
| Target Sequences: | NM_002983 NP_002974.1 |
Publications (2)
1
Chemokine (C-C motif) ligand 3 detection in the serum of persons exposed to asbestos: A patient-based study. Xu J, Alexander DB, Iigo M, Hamano H, Takahashi S, Yokoyama T, Kato M, Usami I, Tokuyama T, Tsutsumi M, Tamura M, Oguri T, Niimi A, Hayashi Y, Yokoyama Y, Tonegawa K, Fukamachi K, Futakuchi M, Sakai Y, Suzui M, Kamijima M, Hisanaga N, Omori T, Nakae D, Hirose A, Kanno J, Tsuda H. Cancer science. 2015 106:825-32. (IHC-P; Human)
[Full Text Article]
[PubMed:25940505]
[PMC:PMC4520633]
2
CCL3-CCR5 axis contributes to progression of esophageal squamous cell carcinoma by promoting cell migration and invasion via Akt and ERK pathways. Takayuki Kodama, Yu-Ichiro Koma, Noriaki Arai, Aya Kido, Naoki Urakawa, Mari Nishio, Manabu Shigeoka, Hiroshi Yokozaki. Laboratory investigation; a journal of technical methods and pathology. 2020 September;100:1140-1157. [Full Text Article]
[PubMed:32457351]
[PMC:PMC7438203]
Related Antibodies: LS-C384561.
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CCL3 / MIP-1-Alpha Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CCL3 / MIP-1-Alpha Rabbit anti-Human Polyclonal (aa59-87) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
CCL3 / MIP-1-Alpha Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
CCL3 / MIP-1-Alpha Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
CCL3 / MIP-1-Alpha Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
CCL3 / MIP-1-Alpha Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
HEK 293 Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
7.8 kDa (SDS-PAGE)
5 µg/$268; 25 µg/$308
Sandwich
96-Well Strip Plate
Dog
7.81 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$854
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$488
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$651
CCL3 / MIP-1-Alpha Mouse anti-Human Monoclonal (4E7) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
CCL3 / MIP-1-Alpha Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, Func, Neut, WB
Unconjugated
100 µg/$798
CCL3 / MIP-1-Alpha Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
CCL3 / MIP-1-Alpha Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$567
CCL3 / MIP-1-Alpha Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P
Unconjugated
250 µl/$548
CCL3 / MIP-1-Alpha Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
CCL3 / MIP-1-Alpha Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
500 µg/$780
Development Kit
200 Wells
Mouse
4 - 1000 pg/ml
Colorimetric - 405nm (ABTS)
1 Test/$180
Sandwich
96-Well Microplate
Human
4.13 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
CCL3 / MIP-1-Alpha Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$842
CCL3 / MIP-1-Alpha Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
CCL3 / MIP-1-Alpha Rabbit anti-Rat Polyclonal (Biotin) Antibody
Rat
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
CCL3 / MIP-1-Alpha Rabbit anti-Rat Polyclonal (PE) Antibody
Rat
ELISA, Neut, WB
PE Conjugated
100 µl/$860
CCL3 / MIP-1-Alpha Rabbit anti-Human Polyclonal (aa26-75) Antibody
Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$460
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