Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
Produced in BALB/c mice using recombinant hEotaxin-3 as the immunizing antigen.
Suitable for use in Neutralization and ELISA. Neutralization: 1-5 ug/ml to yield one-half maximal inhibition [ND50] of the biological activity of Human Eotaxin-3 (2 ug/ml). ELISA:1-2 ug/ml, as a capture antibody in conjunction with a compatible secondary reagent to yield satisfactory results in a sandwich ELISA.
PBS, pH 7.2. No preservative added.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C.
CCL26 / Eotaxin 3 is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils.