Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Protein G purified
Western blot (0.1 - 1 µg/ml)
Specificity and Use
CCL2 / MCP1 antibody was raised against purified recombinant human MCP-1.
Recognizes natural and recombinant human MCP-1. Does not react with human interleukin-8 (IL-8), other human cytokines tested such as interleukin-1B (IL-1B), serum amyloid A (SAA) or epidermal growth factor (EGF).
Suitable for use in ELISA, Neutralization and Western Blot. Western Blot: 0.1-1 ug/ml detects 0.1 ug/lane of human MCP-1.
PBS, pH 7.2, 40% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
CCL2 / MCP1 is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues.