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CCKBR / Cckb
cholecystokinin B receptor
Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism.
| Gene Name: | cholecystokinin B receptor |
| Family/Subfamily: | GPCR , Cholecystokinin |
| Synonyms: | CCKBR, CCKB, Cholecystokinin-2 receptor, CCK-BR, CCK2 receptor, CCK2-R, CCKB-R, Cholecystokinin-B, GASR, CCK-B, CCK-B receptor, CCK2R, Cckb receptor, CCKRB, Cholecystokinin B receptor, Gastrin receptor |
| Target Sequences: | NM_176875 NP_795344.1 P32239 |
Publications (4)
1
Control of somatostatin (SS) secretion by CCK-1 and CCK-2 receptors' occupation in RIN-14B cells, a rat pancreatic islet cell line. El-Kouhen K, Morisset J. Pancreas. 2010 39:127-34. (IF; Rat)
[PubMed:19959964]
Related Antibodies: LS-B2325.
2
Cholecystokinin and Somatostatin Negatively Affect Growth of the Somatostatin-RIN-14B Cells. El-Kouhen K, Morisset J. International journal of endocrinology. 2009 2009:875167.
[PubMed:20011057]
[PMC:PMC2778184]
Related Antibodies: LS-B2325.
3
CCK1 and CCK2 receptors are expressed on pancreatic stellate cells and induce collagen production. Berna MJ, Seiz O, Nast JF, Benten D, Blker M, Koch J, Lohse AW, Pace A. The Journal of biological chemistry. 2010 285:38905-14.
[PubMed:20843811]
[PMC:PMC2998120]
Related Antibodies: LS-B2325.
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Neuroscience
CCKBR / Cckb Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
CCKBR / Cckb Goat anti-Human Polyclonal (aa251-266) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
Neuroscience
Fast Shipping
CCKBR / Cckb Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
CCKBR / Cckb Rabbit anti-Human Polyclonal (aa11-60) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CCKBR / Cckb Rabbit anti-Human Polyclonal (aa206-219) Antibody
Rabbit, Dog, Horse, Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
20 µl/$483; 100 µl/$832
CCKBR / Cckb Rabbit anti-Human Polyclonal (30-110 aa, N-terminal) Antibody
Mouse, Rat, Human, Monkey
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CCKBR / Cckb Rabbit anti-Human Polyclonal Antibody
Human
Flo, ICC, IHC, IHC-Fr, WB
Unconjugated
10 µg/$318; 100 µg/$470
CCKBR / Cckb Rabbit anti-Human Polyclonal (DY488) Antibody
Human
Flo
DY488 Conjugated
100 µg/$571
CCKBR / Cckb Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
CCKBR / Cckb Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$331
CCKBR / Cckb Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
CCKBR / Cckb Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Flo, WB
Unconjugated
100 µg/$575
CCKBR / Cckb Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
CCKBR / Cckb Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rabbit, Bovine, Human, Monkey
IP, WB
Unconjugated
100 µl/$299
CCKBR / Cckb Rabbit anti-Human Polyclonal (aa191-204) Antibody
Bat, Human
WB
Unconjugated
20 µl/$483; 100 µl/$832
CCKBR / Cckb Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CCKBR / Cckb Rabbit anti-Human Polyclonal (aa277-326) Antibody
Human
WB
Unconjugated
100 µl/$424
CCKBR / Cckb Rabbit anti-Human Polyclonal (aa277-326) (HRP) Antibody
Guinea pig, Human, Orangutan
WB
HRP Conjugated
100 µl/$469
CCKBR / Cckb Rabbit anti-Human Polyclonal (Leu54) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
CCKBR / Cckb Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CCKBR / Cckb Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$321
CCKBR / Cckb Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$386
CCKBR / Cckb Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CCKBR / Cckb Rabbit anti-Human Polyclonal (DY550) Antibody
Human
Flo
DY550 Conjugated
100 µg/$571
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