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Anti-CCKBR / Cckb Antibody (aa251-266) IHC-plus™ LS-B2325

Note: This antibody replaces LS-C54625, LS-C79258, LS-B2855


Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml Unavailable

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19 CCKBR / Cckb Antibodies

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Anti-CCKBR / Cckb Antibody (Cytoplasmic Domain) IHC-plus™ LS-A1282
Rabbit Polyclonal to Human CCKBR / Cckb
IHC - Paraffin
Immunohistochemistry Image
Anti-CCKBR / Cckb Antibody (Extracellular Domain) IHC-plus™ LS-A6535
Rabbit Polyclonal to Human CCKBR / Cckb
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Anti-CCKBR / Cckb Antibody (aa251-266) IHC-plus™ LS-B2325
Goat Polyclonal to Human CCKBR / Cckb
IHC - Paraffin, Western blot, ELISA
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Anti-CCKBR / Cckb Antibody (aa11-60) LS-C120565
Rabbit Polyclonal (IgG) to Human CCKBR / Cckb
Human, Mouse, Rat
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Anti-CCKBR / Cckb Antibody (aa206-219) LS-C121614
Rabbit Polyclonal to Human CCKBR / Cckb
Human, Monkey, Bat, Dog, Horse, Rabbit
IHC - Paraffin, Western blot

100% Guaranteed 100% Guaranteed Publications Publications (3)
Goat Polyclonal to Human CCKBR / Cckb
IHC - Paraffin, Western blot, ELISA


Human CCKBR / Cckb
Human (tested or 100% immunogen sequence identity)
Immunoaffinity purified


  • IHC - Paraffin (5 µg/ml)
  • Western blot (0.1 - 0.3 µg/ml)
  • ELISA (1:32000)

Specificity and Use

CCKBR / Cckb antibody was raised against synthetic peptide C-FDGDSDSDSQSRVRNQ from an internal region of human CCKBR (NP_795344.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon (100%); Elephant (94%); Monkey, Hamster (88%); Marmoset, Mouse, Rabbit (81%).
LS-E25883 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B2325. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Human CCKBR.
Immunohistochemistry: LS-B2325 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2325 was determined to be 5 ug/ml.


Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

Publications (3)

Control of somatostatin (SS) secretion by CCK-1 and CCK-2 receptors' occupation in RIN-14B cells, a rat pancreatic islet cell line. El-Kouhen K, Morisset J. Pancreas. 2010 39:127-34. (IF; Rat) [PubMed:19959964]
Cholecystokinin and Somatostatin Negatively Affect Growth of the Somatostatin-RIN-14B Cells. El-Kouhen K, Morisset J. International journal of endocrinology. 2009 2009:875167. [PubMed:20011057] [PMC:PMC2778184]
CCK1 and CCK2 receptors are expressed on pancreatic stellate cells and induce collagen production. Berna MJ, Seiz O, Nast JF, Benten D, Blker M, Koch J, Lohse AW, Pace A. The Journal of biological chemistry. 2010 285:38905-14. [PubMed:20843811] [PMC:PMC2998120]

About CCKBR / Cckb

P32239 NM_176875 NP_795344.1

CCKBR Antibody, CCKB Antibody, Cholecystokinin-2 receptor Antibody, CCK-BR Antibody, CCK2 receptor Antibody, CCK2-R Antibody, CCKB-R Antibody, Cholecystokinin-B Antibody, GASR Antibody, CCK-B Antibody, CCK-B receptor Antibody, CCK2R Antibody, Cckb receptor Antibody, CCKRB Antibody, Cholecystokinin B receptor Antibody, Gastrin receptor Antibody

Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism.


Anti-CCKBR antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2325 concentration 5 ug/ml.

Requested From: 
Date Requested: 4/24/2017

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