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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CCKBR / Cckb Antibody (aa206‑219) LS‑C121614
Antibody
Cckb antibody LS-C121614 is an unconjugated rabbit polyclonal antibody to Cckb (CCKBR) from human, bat, dog and other species. Validated for IHC and WB.
Catalog
Size
Price
LS-C121614-20
20 µl
Unavailable
LS-C121614-100
100 µl
Unavailable

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Product Description

Cckb antibody LS-C121614 is an unconjugated rabbit polyclonal antibody to Cckb (CCKBR) from human, bat, dog and other species. Validated for IHC and WB.
About CCKBR / Cckb
Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism. P32239 NM_176875 NP_795344.1

CCKBR Antibody, CCKB Antibody, Cholecystokinin-2 receptor Antibody, CCK-BR Antibody, CCK2 receptor Antibody, CCK2-R Antibody, CCKB-R Antibody, Cholecystokinin-B Antibody, GASR Antibody, CCK-B Antibody, CCK-B receptor Antibody, CCK2R Antibody, Cckb receptor Antibody, CCKRB Antibody, Cholecystokinin B receptor Antibody, Gastrin receptor Antibody


Specifications

Target
Human CCKBR / Cckb
Host
Rabbit
Reactivity
Human, Monkey, Bat, Dog, Horse, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Bovine, Hamster (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:100)
  • Western blot (1:3000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CCKBR / Cckb antibody was raised against synthetic human CCK-R Type B (aa 206-219) polylysine conjugated(VHRWPSARVRQTWS). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Monkey, Marmoset, Elephant, Bat, Dog, Horse, Rabbit (100%); Gibbon, Hamster, Panda, Bovine (93%); Rat (86%).
Epitope
aa206-219
Specificity
Recognizes human Cholecystokinin-Receptor Type B (Epitope: aa206-219).
Usage
Suitable for use in Western Blot and Immunohistochemistry. Western Blot 1:3000. Immunohistochemistry: (paraffin): 1:100.
Presentation
Lyophilized from in PBS, pH 7.2
Reconstitution
20 µl or 100 µl Sterile ddH2O
Storage
Lyophilized powder may be stored at -20°C. Aliquot and store at -20°C. Reconstituted product is stable for 1 year at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/19/2018

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