Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Monkey (tested or 100% immunogen sequence identity)
IHC - Paraffin
IHC - Paraffin
Specificity and Use
CCKAR / CCK1R antibody was raised against synthetic peptide C-FEASQKKSAKERKPST from an internal region of human CCKAR (NP_000721.1). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset (100%); Gibbon (94%); Rat, Elephant, Rabbit (88%); Bat, Horse, Guinea pig (81%).
LS-E25884 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C54624. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.