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Anti-CBX5 / HP1 Alpha Antibody (aa88-102) IHC-plus™ LS-B2394

Note: This antibody replaces LS-C54619, LS-C67842

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CBX5 / HP1 Alpha Antibodies

Anti-CBX5 / HP1 Alpha Antibody (aa67-119) LS-C24207
Mouse Monoclonal (IgG) to Mouse CBX5 / HP1 Alpha
Mouse, Human
IHC, ICC, Western blot, ELISA
Unconjugated
Anti-CBX5 / HP1 Alpha Antibody (aa88-102) IHC-plus™ LS-B2394
Goat Polyclonal to Human CBX5 / HP1 Alpha
Human, Monkey, Bovine, Horse, Pig, Sheep
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-CBX5 / HP1 Alpha Antibody LS-C123746
Mouse Monoclonal (IgG1,k) to Mouse CBX5 / HP1 Alpha
Mouse, Human
IHC, ICC, ELISA
Unconjugated

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human CBX5 / HP1 Alpha
Human, Monkey, Bovine, Horse, Pig, Sheep
IHC - Paraffin, Western blot, ELISA
Unconjugated

Details

Human CBX5 / HP1 Alpha
Goat
Human, Monkey, Bovine, Horse, Pig, Sheep (tested or 100% immunogen sequence identity)
Mouse, Rat, Dog, Hamster, Rabbit (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (2.5 µg/ml)
  • Western blot (1:128000) & (0.03 - 0.1 µg/ml)
  • ELISA (1:128000)

Specificity and Use

CBX5 / HP1 Alpha antibody was raised against synthetic peptide C-NKRKSNFSNSADDIK from an internal region of human CBX5 / HP1 (NP_036249.1; NP_001120793.1; NP_001120794.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Sheep, Bovine, Horse, Pig (100%); Mouse, Rat, Hamster, Elephant, Panda, Dog, Rabbit (93%); Bat (87%).
LS-E25964 - Lyophilized - 100 µg - $145.00
aa88-102
Human CBX5 / HP1. Variants (NP_036249.1; NP_001120793.1; NP_001120794.1) encode the same protein.
Immunohistochemistry: LS-B2394 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2394 was determined to be 2.5 ug/ml.

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About CBX5 / HP1 Alpha

P45973 NM_012117 NP_036249.1

CBX5 Antibody, Chromobox homolog 5 Antibody, HP1Hs alpha Antibody, HP1Hs-alpha Antibody, HP1 Antibody, HP1 alpha homolog Antibody, HP1 alpha Antibody, HP1-ALPHA Antibody, HP1A Antibody, Antigen p25 Antibody, Chromobox protein homolog 5 Antibody

CBX5 / HP1 Alpha is a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins.

Immunohistochemistry

Immunohistochemistry
Anti-CBX5 / HP1 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2394 concentration 5 ug/ml.

Western blot

Western blot
Antibody (0.03 ug/ml) staining of Hela lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Requested From: United States
Date Requested: 12/6/2016

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