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Anti-CBX4 Antibody (N-Terminus) LS-C153640

Ordering

Wt. Vol. Conc. Price
100 µg - - Unavailable

Most Popular CBX4 Antibodies

Anti-CBX4 Antibody (aa95-107) IHC-plus™ LS-B128
Rabbit Polyclonal (IgG) to Human CBX4
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-CBX4 Antibody IHC-plus™ LS-B8138
Rabbit Polyclonal (IgG) to Human CBX4
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-CBX4 Antibody (aa53-102) IHC-plus™ LS-B11869
Rabbit Polyclonal (IgG) to Human CBX4
Human, Monkey, Mouse, Bovine, Dog, Guinea pig, Pig, Rabbit
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human CBX4
Human
Western blot
Unconjugated

Details

Human CBX4
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot (1 - 2 µg/ml)

Specificity and Use

CBX4 antibody was raised against a 17 amino acid peptide near the amino terminus of human CBX4.
LS-E31322 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-C153640. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
N-Terminus
Human CBX4. Two alternatively spliced transcript variants have been observed.
CBX4 antibody can be used for detection of CBX4 by Western blot at 1-2 ug/mL.

Packaging

PBS, 0.02% sodium azide
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About CBX4

O00257 NM_003655 NP_003646.2

CBX4 Antibody, Chromobox homolog 4 Antibody, Chromobox protein homolog 4 Antibody, E3 SUMO-protein ligase CBX4 Antibody, NBP16 Antibody, NS5ATP1-binding protein 16 Antibody, HPC2 Antibody, Polycomb 2 homolog Antibody, PC2 Antibody, Pc class 2 homolog Antibody

E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131.Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.

Immunofluorescence

Immunofluorescence
Immunofluorescence of CBX4 in human brain tissue with CBX4 antibody at 20 ug/ml.

Western blot

Western blot
Western blot analysis of CBX4 in human brain tissue lysate with CBX4 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

Requested From: 
Date Requested: 3/30/2017

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