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CBX4

chromobox homolog 4

E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131.Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Gene Name: chromobox homolog 4
Synonyms: CBX4, Chromobox homolog 4, Chromobox protein homolog 4, E3 SUMO-protein ligase CBX4, NBP16, NS5ATP1-binding protein 16, HPC2, Polycomb 2 homolog, PC2, Pc class 2 homolog
Target Sequences: NM_003655 NP_003646.2 O00257

☰ Filters
Antibodies (43)
Proteins (1)
Primary (43)
Recombinant (1)
CBX4 (44)
Human (43)
Mouse (21)
Rat (6)
Bat (3)
Bovine (6)
Chicken (3)
Chimpanzee (6)
Dog (6)
Gibbon (6)
Guinea pig (6)
Horse (3)
Monkey (7)
Pig (6)
Rabbit (6)
Xenopus (3)
IHC (19)
IHC-P (9)
WB (40)
Flo (1)
ELISA (24)
ICC (6)
IF (9)
IP (4)
Peptide-ELISA (1)
rabbit (41)
mouse (1)
rabbit-new zealand white (1)
Product Group
IHCPlus (4)
IgG (31)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (42)
6C5G3 (1)
APC Conjugated (3)
Azide-free (3)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (22)
aa1-30 (7)
aa410-437 (7)
aa80-110 (7)
aa31-80 (4)
aa53-102 (4)
aa100-150 (1)
aa150-200 (1)
aa401-560 (1)
No (44)
GST (1)
Human (1)
Wheat Germ Extract (1)
Purified (1)
CBX4 Antibody - Immunohistochemistry of paraffin-embedded human lung cancer tissue.
Select
CBX4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CBX4 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
Select
CBX4 Rabbit anti-Human Polyclonal (aa401-560) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
CBX4 Antibody - Anti-CBX4 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CBX4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$515
Select
CBX4 Rabbit anti-Human Polyclonal (aa80-110) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
200 µl/$734
Select
CBX4 Rabbit anti-Human Polyclonal (aa80-110) (Biotin) Antibody
Mouse, Human
ELISA, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
Select
CBX4 Rabbit anti-Human Polyclonal (aa80-110) (FITC) Antibody
Mouse, Human
ELISA, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
Select
CBX4 Rabbit anti-Human Polyclonal (aa80-110) (APC) Antibody
Mouse, Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
Select
CBX4 Rabbit anti-Human Polyclonal (aa80-110) (PE) Antibody
Mouse, Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
Select
CBX4 Rabbit anti-Human Polyclonal (aa80-110) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
CBX4 Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
CBX4 Rabbit anti-Human Polyclonal (aa150-200) Antibody
Mouse, Human
IHC, IHC-P
Unconjugated
50 µl/$460
CBX4 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CBX4 Rabbit anti-Human Polyclonal (aa53-102) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
CBX4 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CBX4 Rabbit anti-Human Polyclonal (aa53-102) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
CBX4 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CBX4 Rabbit anti-Human Polyclonal (aa53-102) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
CBX4 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CBX4 Rabbit anti-Human Polyclonal (aa53-102) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
CBX4 Antibody - Anti-HPC2 / CBX4 antibody IHC of human brain, cortex neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Select
CBX4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
Select
CBX4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
CBX4 Antibody - Immunofluorescent analysis of CBX4 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
Select
CBX4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
CBX4 Antibody - Immunofluorescence of CBX4 in human brain tissue with CBX4 antibody at 20 ug/ml.
Select
CBX4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
0.1 mg/$460
Select
CBX4 Mouse anti-Human Monoclonal (6C5G3) Antibody
Human
ELISA, Flo
Unconjugated
100 µl/$459
CBX4 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Select
CBX4 Rabbit anti-Human Polyclonal (aa80-110) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
Select
CBX4 Rabbit-New Zealand White anti-Mouse Polyclonal (aa100-150) Antibody
Mouse, Human
IHC, WB
Unconjugated
100 µl/$393
Select
CBX4 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
Select
CBX4 Rabbit anti-Human Polyclonal (aa410-437) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
CBX4 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
CBX4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-25 of 44 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).