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CBX3 / HP1 Gamma

chromobox homolog 3

Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the mehtyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1.

Gene Name: chromobox homolog 3
Synonyms: CBX3, Chromobox homolog 3, HP1Hs-gamma, Heterochromatin-like protein 1, Modifier 2 protein, HP1-GAMMA, Chromobox protein homolog 3, HECH, HP1 gamma, HP1 gamma homolog
Target Sequences: NM_016587 NP_057671.2 Q13185

☰ Filters
Antibodies (72)
ELISA Kits (14)
Proteins (10)
Cell-Based (1)
Cell-Based Phosphorylation (1)
Competitive EIA (1)
Over-Expression Lysate (4)
Primary (72)
Recombinant (6)
Sandwich (11)
CBX3 / HP1 Gamma (96)
Human (69)
Mouse (55)
Rat (27)
Bat (9)
Bovine (9)
Chicken (4)
Chimpanzee (6)
Dog (9)
Gibbon (6)
Guinea pig (8)
Hamster (9)
Horse (9)
Monkey (11)
Orangutan (6)
Pig (5)
Porcine (1)
Rabbit (9)
Sheep (1)
IHC (28)
IHC-P (23)
WB (62)
Flo (1)
ELISA (17)
ICC (5)
IF (10)
IP (11)
Peptide-ELISA (5)
rabbit (52)
mouse (17)
goat (2)
rabbit-new zealand white (1)
Product Group
IHCPlus (5)
PathPlus Other (1)
IgG (35)
IgG1 (4)
IgG2a,k (6)
monoclonal mc (17)
polyclonal pc (55)
1G12-1D9 (1)
4F4 (1)
6A4 (1)
6D1C4 (1)
96-Well Microplate (4)
96-Well Strip Plate (10)
APC (2)
APC Conjugated (3)
Biotin Conjugated (7)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (3)
Preservative Free (1)
Unconjugated (43)
aa1-183 (16)
aa61-110 (4)
aa71-120 (4)
pSer93 (3)
30-110 aa (2)
aa133-C-term (2)
pSer83 (2)
Internal (1)
Internal Region (1)
aa1-50 (1)
aa114-173 (1)
aa17-173 (1)
aa2-15 (1)
aa59-108 (1)
aa74-87 (1)
aa75-125 (1)
p93 (1)
No (96)
Adherent Cell Cultures (2)
Cell Lysates (1)
Plasma (6)
Serum (6)
Tissue Homogenates (3)
GST (1)
His (3)
His, N-Terminal (1)
Myc-DDK (Flag) (5)
Human (7)
Mouse (1)
293T Cells (2)
E. coli (4)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (2)
CBX3 / HP1 Gamma Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CBX3 / HP1 Gamma Mouse anti-Human Monoclonal Antibody
Mouse, Human
ICC, IHC-P, IP, WB
Unconjugated
50 µl/$460
CBX3 / HP1 Gamma Antibody - Anti-CBX3 / HP1 Gamma antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CBX3 / HP1 Gamma Rabbit anti-Mouse Polyclonal (aa2-15) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µg/$460
CBX3 / HP1 Gamma Antibody - Anti-CBX3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CBX3 / HP1 Gamma Goat anti-Human Polyclonal (aa74-87) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
CBX3 / HP1 Gamma Antibody - Immunohistochemistry - Anti-HP1 gamma Picoband antibody
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CBX3 / HP1 Gamma Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CBX3 / HP1 Gamma Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CBX3 / HP1 Gamma Rabbit anti-Human Polyclonal (aa133-C-term) Antibody
Mouse, Human
IHC, IHC-P
Unconjugated
50 µl/$460
CBX3 / HP1 Gamma Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CBX3 / HP1 Gamma Rabbit anti-Human Polyclonal (aa61-110) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
CBX3 / HP1 Gamma Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CBX3 / HP1 Gamma Rabbit anti-Human Polyclonal (aa75-125) Antibody
Human
IHC, IHC-P, IP
Unconjugated
50 µl/$460
CBX3 / HP1 Gamma Antibody
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CBX3 / HP1 Gamma Rabbit anti-Human Polyclonal Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
ICC, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$423
CBX3 / HP1 Gamma Antibody - Anti-CBX3 rabbit polyclonal antibody at 1:500 dilution. Lane A: HepG2 Whole Cell Lysate. Lane B: Hela Whole Cell Lysate. Lane C: A431 Whole Cell Lysate. Lane D: MCF7 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 20 kDa. Observed band size: 20 kDa. (We are unsure as to the identity of these extra bands.)
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CBX3 / HP1 Gamma Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF, IP, WB
Unconjugated, Preservative Free
100 µl/$412
CBX3 / HP1 Gamma Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Select
CBX3 / HP1 Gamma Mouse anti-Human Monoclonal (1G12-1D9) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$705
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CBX3 / HP1 Gamma Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IF, WB
Biotin Conjugated
100 µl/$904
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CBX3 / HP1 Gamma Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IF, WB
PE Conjugated
100 µl/$904
CBX3 / HP1 Gamma Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using CBX3 Polyclonal Antibody at dilution of 1:40.
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CBX3 / HP1 Gamma Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CBX3 / HP1 Gamma Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using HP1 gamma Antibody. The picture on the right is blocked with the synthesized peptide.
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CBX3 / HP1 Gamma Rabbit anti-Human Polyclonal (aa59-108) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CBX3 / HP1 Gamma Antibody - Immunohistochemical analysis of HP1 gamma staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected with HRP and DAB as chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CBX3 / HP1 Gamma Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
CBX3 / HP1 Gamma Antibody - Immunohistochemical analysis of paraffin-embedded Prostate Cancer using HP1-gamma mouse mAb (1:200 dilution).Antigen retrieval was performed by pressure cooking in citrate buffer (pH 6.0).
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CBX3 / HP1 Gamma Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Hamster, Human, Monkey
ELISA, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
CBX3 / HP1 Gamma Antibody - Immunofluorescence staining of CBX3 in HeLa cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human CBX3 polyclonal antibody (dilution ratio 1:1000) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green).
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CBX3 / HP1 Gamma Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
100 µl/$412
CBX3 / HP1 Gamma Antibody - Staining K562 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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CBX3 / HP1 Gamma Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
CBX3 / HP1 Gamma Rabbit anti-Human Polyclonal (30-110 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
CBX3 / HP1 Gamma Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
Select
CBX3 / HP1 Gamma Mouse anti-Human Monoclonal (aa17-173) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
200 µg/$995
CBX3 / HP1 Gamma Antibody - Western blot of recombinant CBX3 / HP1 Gamma.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CBX3 / HP1 Gamma Rabbit anti-Human Polyclonal (aa1-183) Antibody
Mouse, Human
ICC, IP, WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
CBX3 / HP1 Gamma Antibody - Western blot of HP1gamma antibody
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CBX3 / HP1 Gamma Rabbit anti-Human Polyclonal (30-110 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CBX3 / HP1 Gamma Antibody - Western blot analysis of extracts from 293 cells, using HP1? (Ab-93) antibody.
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CBX3 / HP1 Gamma Rabbit anti-Human Polyclonal (p93) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
Viewing 1-25 of 96 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).