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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CBX1 / HP1 Beta Antibody (aa128‑155) LS‑C168361
HP1 Beta antibody LS-C168361 is an unconjugated rabbit polyclonal antibody to human HP1 Beta (CBX1). Validated for Flow, IHC and WB.
Catalog
Size
Price
LS-C168361-400
400 µl
Unavailable

Popular CBX1 / HP1 Beta Products

Antibody
Species: Mouse, Human
Applications: IHC, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Anti-CBX1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2395 concentration 5 ug/ml.
Species: Human, Monkey, Mouse, Bat, Bovine, Dog, Hamster, Horse, Pig
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Antibody
Species: Human
Applications: ICC, Immunofluorescence, Western blot, Immunoprecipitation
Antibody
Species: Human
Applications: IHC, Immunofluorescence, Western blot, Flow Cytometry, ELISA

Product Description

HP1 Beta antibody LS-C168361 is an unconjugated rabbit polyclonal antibody to human HP1 Beta (CBX1). Validated for Flow, IHC and WB.
About CBX1 / HP1 Beta
CBX1 / HP1 Beta is a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. P83916 NM_006807 NP_006798.1

CBX1 Antibody, CBX Antibody, Chromobox protein homolog 1 Antibody, HP1 beta Antibody, HP1Hs-beta Antibody, Heterochromatin protein 1-beta Antibody, HP1Hsbeta Antibody, M31 Antibody, Modifier 1 protein Antibody, MOD1 Antibody, HP1 beta homolog Antibody, HP1-BETA Antibody, Chromobox homolog 1 Antibody, Heterochromatin protein p25 Antibody, p25beta Antibody


Specifications

Target
Human CBX1 / HP1 Beta
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Mouse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)
  • Flow Cytometry (1:10 - 1:50)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Blocking Peptide
LS-E9851 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C168361. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa128-155
Specificity
This CBX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-155 amino acids from the C-terminal region of human CBX1.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

CBX1 Antibody IHC of formalin-fixed and paraffin-embedded brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
CBX1 Antibody IHC of formalin-fixed and paraffin-embedded brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

Western blot of CBX1 Antibody in MCF-7, A2058, Y79 cell line lysates (35 ug/lane). CBX1 (arrow) was detected using the purified antibody.
Western blot of CBX1 Antibody in MCF-7, A2058, Y79 cell line lysates (35 ug/lane). CBX1 (arrow) was detected using the purified antibody.

Flow Cytometry

CBX1 Antibody flow cytometry of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
CBX1 Antibody flow cytometry of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Immunohistochemistry

CBX1 Antibody IHC of formalin-fixed and paraffin-embedded brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
CBX1 Antibody IHC of formalin-fixed and paraffin-embedded brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

Western blot of CBX1 Antibody in MCF-7, A2058, Y79 cell line lysates (35 ug/lane). CBX1 (arrow) was detected using the purified antibody.
Western blot of CBX1 Antibody in MCF-7, A2058, Y79 cell line lysates (35 ug/lane). CBX1 (arrow) was detected using the purified antibody.

Flow Cytometry

CBX1 Antibody flow cytometry of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
CBX1 Antibody flow cytometry of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Immunohistochemistry

CBX1 Antibody IHC of formalin-fixed and paraffin-embedded brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
CBX1 Antibody IHC of formalin-fixed and paraffin-embedded brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

Western blot of CBX1 Antibody in MCF-7, A2058, Y79 cell line lysates (35 ug/lane). CBX1 (arrow) was detected using the purified antibody.
Western blot of CBX1 Antibody in MCF-7, A2058, Y79 cell line lysates (35 ug/lane). CBX1 (arrow) was detected using the purified antibody.

Flow Cytometry

CBX1 Antibody flow cytometry of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
CBX1 Antibody flow cytometry of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Immunohistochemistry

CBX1 Antibody IHC of formalin-fixed and paraffin-embedded brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
CBX1 Antibody IHC of formalin-fixed and paraffin-embedded brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

Western blot of CBX1 Antibody in MCF-7, A2058, Y79 cell line lysates (35 ug/lane). CBX1 (arrow) was detected using the purified antibody.
Western blot of CBX1 Antibody in MCF-7, A2058, Y79 cell line lysates (35 ug/lane). CBX1 (arrow) was detected using the purified antibody.

Flow Cytometry

CBX1 Antibody flow cytometry of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
CBX1 Antibody flow cytometry of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.


Requested From: 
Date Requested: 6/18/2018

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