CBFB

core-binding factor, beta subunit

CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters. Alternative splicing generates two mRNA variants, each encoding a distinct carboxyl terminus. In some cases, a pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript consisting of the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain 11. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Two transcript variants encoding different isoforms have been found for this gene.

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Products

Antibodies (53)

Proteins (11)

Type

Over-Expression Lysate (4)

Primary (53)

Recombinant (7)

Target

CBFB (64)

Reactivity

Human (53)

Mouse (21)

Rat (8)

Bovine (3)

Chicken (1)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (1)

Horse (1)

Monkey (4)

Orangutan (3)

Pig (4)

Rabbit (4)

Zebrafish (4)

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Application

IHC (12)

IHC-P (6)

WB (46)

Flo (1)

DB (2)

ELISA (17)

ICC (4)

IF (9)

IP (4)

Peptide-ELISA (3)

Host

rabbit (49)

mouse (3)

goat (1)

Product Group

IHCPlus (1)

Isotype

IgG (22)

IgG1 (2)

IgM (1)

Clonality

monoclonal mc (3)

polyclonal pc (50)

Clone

122 (1)

344C3a (2)

Format

APC (2)

APC Conjugated (3)

Azide-free (1)

Biotin Conjugated (5)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (3)

Preservative Free (1)

Unconjugated (28)

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Epitope

aa1-182 (9)

aa1-187 (8)

aa61-90 (7)

N-Terminus (5)

30-110 aa, N-terminal (1)

Arg33 (1)

aa1-50 (1)

aa11-60 (1)

aa165-177 (1)

aa166-182 (1)

aa166-187 (1)

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Publications

No (64)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His-SUMO (1)

His-T7 (2)

Myc-DDK (Flag) (5)

Species

Human (8)

Mouse (1)

Source

293T Cells (2)

E. coli (4)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (2)

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CBFB Antibody (clone 344C3a) LS-C342588

Antibody:

CBFB Mouse anti-Human Monoclonal (344C3a) Antibody

Reactivity:

Human

Applications:

DB, ICC, IF, WB

Format:

Unconjugated

Price:

100 µg/$486

Select

CBFB Antibody (aa61-90) LS-C168351

Antibody:

CBFB Rabbit anti-Human Polyclonal (aa61-90) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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CBFB Antibody (N-Terminus) LS-C368668

Antibody:

CBFB Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Zebrafish, Pig, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

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IHC-plus™ CBFB Antibody (aa11-60) LS-B7059

(4.0) Rating

Antibody:

CBFB Rabbit anti-Human Polyclonal (aa11-60) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

CBFB Antibody LS-C804545

Antibody:

CBFB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

CBFB Antibody LS-C662499

Antibody:

CBFB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

CBFB Antibody (30-110 aa, N-terminal) LS-C385435

Antibody:

CBFB Rabbit anti-Human Polyclonal (30-110 aa, N-terminal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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CBFB Antibody LS-C333969

Antibody:

CBFB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

CBFB Antibody (Arg33) LS-C176931

Antibody:

CBFB Rabbit anti-Human Polyclonal (Arg33) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

CBFB Antibody LS-C765137

Antibody:

CBFB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

CBFB Antibody LS-C831946

Antibody:

CBFB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

CBFB Antibody (Preservative Free) LS-C815540

Antibody:

CBFB Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ICC, IF, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

Select

CBFB Antibody LS-C822918

Antibody:

CBFB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

CBFB Antibody (clone 344C3a) LS-C184552

Antibody:

CBFB Mouse anti-Human Monoclonal (344C3a) Antibody

Reactivity:

Human

Applications:

DB, ICC, WB

Format:

Unconjugated

Price:

50 µg/$474

Select

CBFB Antibody (aa1-182) LS-C377574

Antibody:

CBFB Rabbit anti-Human Polyclonal (aa1-182) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

CBFB Antibody LS-C484045

Antibody:

CBFB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µl/$412

Select

CBFB Antibody (aa61-90) LS-C327106

Antibody:

CBFB Rabbit anti-Human Polyclonal (aa61-90) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

CBFB Antibody (aa61-90, Biotin) LS-C206477

Antibody:

CBFB Rabbit anti-Human Polyclonal (aa61-90) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

CBFB Antibody (aa61-90, FITC) LS-C206478

Antibody:

CBFB Rabbit anti-Human Polyclonal (aa61-90) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

CBFB Antibody (aa61-90, Azide-free, HRP) LS-C207953

Antibody:

CBFB Rabbit anti-Human Polyclonal (aa61-90) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

CBFB Antibody (aa61-90, APC) LS-C206476

Antibody:

CBFB Rabbit anti-Human Polyclonal (aa61-90) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

CBFB Antibody (aa61-90, PE) LS-C206480

Antibody:

CBFB Rabbit anti-Human Polyclonal (aa61-90) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

Select

CBFB Antibody (aa166-187) LS-C290216

Antibody:

CBFB Rabbit anti-Human Polyclonal (aa166-187) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

CBFB Antibody (aa166-182) LS-C290215

Antibody:

CBFB Rabbit anti-Human Polyclonal (aa166-182) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

CBFB Antibody (aa165-177) LS-C204982

Antibody:

CBFB Goat anti-Human Polyclonal (aa165-177) Antibody

Reactivity:

Chicken, Rabbit, Mouse, Guinea pig, Horse, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

Viewing 1-25 of 64 product results

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