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Anti-CBFA2T2 / MTGR1 Antibody (aa401-604) LS-C186028

Ordering

Wt. Vol. Conc. Price
- 100 µl 1 mg/ml $335
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular CBFA2T2 / MTGR1 Antibodies

Anti-CBFA2T2 / MTGR1 Antibody (aa1-30, Biotin) LS-C253471
Rabbit Polyclonal (IgG) to Human CBFA2T2 / MTGR1
Human
Western blot, ELISA
Biotin Conjugated
Anti-CBFA2T2 / MTGR1 Antibody (C-Terminus) IHC-plus™ LS-B11988
Rabbit Polyclonal (IgG) to Human CBFA2T2 / MTGR1
Human, Monkey, Bovine, Dog, Guinea pig, Horse, Pig, Chicken
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-CBFA2T2 / MTGR1 Antibody LS-C346193
Rabbit Polyclonal (IgG) to Human CBFA2T2 / MTGR1
Human, Mouse, Rat
IHC, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry - Paraffin Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human CBFA2T2 / MTGR1
Human
ICC, Western blot
Unconjugated

Details

Human CBFA2T2 / MTGR1
Rabbit
Human (tested or 100% immunogen sequence identity)
Mouse, Rat (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • ICC (1:100 - 1:1000)
  • Western blot (1:500 - 1:3000)

Specificity and Use

CBFA2T2 / MTGR1 antibody was raised against recombinant fragment corresponding to a region within amino acids 401 and 604 of CBFA2T2 (SwissProt O43439). Percent identity by BLAST analysis: Human (100%); Mouse, Rat (95%); Chicken (80%).
aa401-604
Human MTGR1

Packaging

0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal
Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
For research use only.

About CBFA2T2 / MTGR1

O43439 NM_005093 NP_005084.1

CBFA2T2 Antibody, Brain mtgr1 mrna, partial 5' Antibody, EHT Antibody, ETO homolog on chromosome 20 Antibody, MTGR1 Antibody, p85 Antibody, MTG8-like protein Antibody, MTG8-related protein 1 Antibody, Translocated to, 2 Antibody, Protein CBFA2T2 Antibody, ZMYND3 Antibody

In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation.

Immunocytochemistry

Immunocytochemistry
Immunofluorescence of paraformaldehyde-fixed HeLa using CBFA2T2 antibody at 1:200 dilution.

Western blot

Western blot
Sample (30 ug of whole cell lysate). A: Hep G2 . 7.5% SDS PAGE. MTGR1 antibody diluted at 1:1000.

Requested From: United States
Date Requested: 12/7/2016

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