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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CBFA1 / RUNX2 Antibody (phospho‑Ser465) LS‑C97081
RUNX2 antibody LS-C97081 is an unconjugated rabbit polyclonal antibody to human RUNX2 (CBFA1). Validated for DB.
Catalog
Size
Price
LS-C97081-400
400 µl
Unavailable

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Product Description

RUNX2 antibody LS-C97081 is an unconjugated rabbit polyclonal antibody to human RUNX2 (CBFA1). Validated for DB.
About CBFA1 / RUNX2
Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. Q13950 NM_004348 NP_004339.3

RUNX2 Antibody, AML3 Antibody, CCD Antibody, CCD1 Antibody, OSF2 Antibody, PEBP2A1 Antibody, PEBP2A2 Antibody, PEA2-alpha A Antibody, PEBP2-alpha A Antibody, OSF-2 Antibody, PEBP2A Antibody, PEBP2aA1 Antibody, CBF-alpha-1 Antibody, CBFA1 Antibody, Oncogene AML-3 Antibody, PEA2aA Antibody, PEBP2aA Antibody


Specifications

Target
Human CBFA1 / RUNX2
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Dot Blot (1:500)
Blocking Peptide
LS-E7419 - Lyophilized - 100 µg - $230.00
Immunizing peptide used to generate LS-C97081. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
pSer465
Specificity
This RUNX2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S465 of human RUNX2.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Dot Blot

Dot blot of anti-Phospho-RUNX2-pS465 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
Dot blot of anti-Phospho-RUNX2-pS465 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Dot Blot

Dot blot of anti-Phospho-RUNX2-pS465 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
Dot blot of anti-Phospho-RUNX2-pS465 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Dot Blot

Dot blot of anti-Phospho-RUNX2-pS465 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
Dot blot of anti-Phospho-RUNX2-pS465 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Dot Blot

Dot blot of anti-Phospho-RUNX2-pS465 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
Dot blot of anti-Phospho-RUNX2-pS465 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.


Requested From: 
Date Requested: 6/19/2018

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