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Anti-CASR/Calcium Sensing Receptor Antibody (N-Terminus, clone HL 1499) IHC-plus™ LS-B78

Note: This antibody replaces LS-C2628, LS-C77549


Wt. Vol. Conc. Price
- 100 µl 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular CASR/Calcium Sensing Receptor Antibodies

Anti-CASR/Calcium Sensing Receptor Antibody (N-Terminus, clone HL 1499) IHC-plus™ LS-B78
Mouse Monoclonal [clone HL 1499] (IgG1,k) to Human CASR/Calcium Sensing Receptor
Human, Mouse, Rat, Rabbit
IHC - Paraffin, IHC - Frozen, ICC, Western blot, Immunoprecipitation, Flow Cytometry, Radioimmunoassay
Immunohistochemistry Image
Anti-CASR/Calcium Sensing Receptor Antibody (aa214-235, clone ADD) IHC-plus™ LS-B7687
Mouse Monoclonal [clone ADD] (IgG2a) to Human CASR/Calcium Sensing Receptor
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken
IHC - Paraffin, IHC - Frozen, Western blot
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone HL 1499] (IgG1,k) to Human CASR/Calcium Sensing Receptor
Human, Mouse, Rat, Rabbit
IHC - Paraffin, IHC - Frozen, ICC, Western blot, Immunoprecipitation, Flow Cytometry, Radioimmunoassay (applications tested for the base form of this product only)


Human CASR/Calcium Sensing Receptor
Human, Mouse, Rat, Rabbit (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [HL 1499]
Protein G purified


  • IHC - Paraffin (10 µg/ml)
  • IHC - Frozen (1:50 - 1:200)
  • ICC (1:50 - 1:200)
  • Western blot (1:50 - 1:200)
  • Immunoprecipitation
  • Flow Cytometry (1 µg/10E6 cells)
  • Radioimmunoassay
  • (applications tested for the base form of this product only)

Specificity and Use

CASR/Calcium Sensing Receptor antibody was raised against n-terminal, extracellular region of human Calcium Sensing Receptor (see reference 2)
Calcium Sensing Receptor protein.
Immunohistochemistry: LS-B78 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B78 was determined to be 10 ug/ml.


Tris-glycine buffer, 150 mM sodium chloride, 0.05% sodium azide.
Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
For research use only.

About CASR/Calcium Sensing Receptor

P41180 NM_000388 NP_000379.2

CASR Antibody, Ca sensing receptor Antibody, Ca2+ sensing receptor Antibody, Calcium-sensing receptor Antibody, FIH Antibody, EIG8 Antibody, GPRC2A Antibody, HHC Antibody, HHC1 Antibody, Hypocalciuric hypercalcemia 1 Antibody, PCAR1 Antibody, NSHPT Antibody, CAR Antibody, FHH Antibody

CASR, a Calcium-Sensing Receptor, functions as a sensor in parathyroid and kidney to determine extracellular calcium concentration and to maintain calcium homeostasis. This receptor regulates both secretion of parathyroid hormone and excretion of urinary calcium. Mutations that inactivate CASR cause familial hypocalciuric hypercalcemia, which is also correlated with hyperparathyroidism. On the other hand, mutations that activate CASR cause autosomal dominant hypocalcemia. Hjalm et al.


Anti-Calcium Sensing Receptor antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B78 concentration 10 ug/ml. This image was taken for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.

Requested From: United States
Date Requested: 10/27/2016

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