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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CASR/Calcium Sensing Receptor Antibody (aa214‑235, clone ADD) IHC‑plus™ LS‑B7687
Note: This antibody replaces LS-C77550
Calcium Sensing Receptor antibody LS-B7687 is an unconjugated mouse monoclonal antibody to Calcium Sensing Receptor (CASR) from human, mouse, rat and other species. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B7687-50
50 µg (1 mg/ml)
Unavailable

Popular CASR/Calcium Sensing Receptor Products

Anti-CASR/Calcium Sensing Receptor antibody IHC of human Thyroid, Medullary Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken
Applications: IHC, IHC - Paraffin
Anti-Calcium Sensing Receptor antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B78 concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IHC of paraffin-embedded human brain tissue, using Calcium Sensing Receptor (Ab-888) Antibody. The picture on the right is treated with the synthesized peptide.
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Product Description

Calcium Sensing Receptor antibody LS-B7687 is an unconjugated mouse monoclonal antibody to Calcium Sensing Receptor (CASR) from human, mouse, rat and other species. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.
About CASR/Calcium Sensing Receptor
CASR, a Calcium-Sensing Receptor, functions as a sensor in parathyroid and kidney to determine extracellular calcium concentration and to maintain calcium homeostasis. This receptor regulates both secretion of parathyroid hormone and excretion of urinary calcium. Mutations that inactivate CASR cause familial hypocalciuric hypercalcemia, which is also correlated with hyperparathyroidism. On the other hand, mutations that activate CASR cause autosomal dominant hypocalcemia. Hjalm et al. P41180 NM_000388 NP_000379.2

CASR Antibody, Ca sensing receptor Antibody, Ca2+ sensing receptor Antibody, Calcium-sensing receptor Antibody, FIH Antibody, EIG8 Antibody, GPRC2A Antibody, HHC Antibody, HHC1 Antibody, Hypocalciuric hypercalcemia 1 Antibody, PCAR1 Antibody, NSHPT Antibody, CAR Antibody, FHH Antibody


Specifications

Target
Human CASR/Calcium Sensing Receptor
Host
Mouse
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken (tested or 100% immunogen sequence identity)
Predicted
Xenopus (at least 90% immunogen sequence identity)
Clonality
IgG2a Monoclonal [ADD]
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • IHC - Frozen (2 µg/ml)
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide: ADDDYGRPGIEKFREEAEERDI, corresponding to amino acids 214-235 of Human Calcium Sensing Receptor. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus (100%); Xenopus (95%); Stickleback, Pufferfish (86%).
Epitope
aa214-235
Specificity
Species cross-reactivity: Cross-reacts with Human, Rat and bovine.
Usage
Suitable for use in Western Blot and Immunohistochemistry.
Presentation
PBS, 1 mg/ml BSA, 0.05% sodium azide.
Storage
Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Anti-FIH / CASR antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7687 dilution 5 ug/ml.
Anti-FIH / CASR antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7687 dilution 5 ug/ml.

Immunohistochemistry

Anti-FIH / CASR antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7687 dilution 5 ug/ml.
Anti-FIH / CASR antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7687 dilution 5 ug/ml.

Immunohistochemistry

Anti-FIH / CASR antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7687 dilution 5 ug/ml.
Anti-FIH / CASR antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7687 dilution 5 ug/ml.

Immunohistochemistry

Anti-FIH / CASR antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7687 dilution 5 ug/ml.
Anti-FIH / CASR antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7687 dilution 5 ug/ml.


Requested From: 
Date Requested: 6/19/2018

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