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Anti-CASP8AP2 / FLASH Antibody (C-Terminus) LS-C15224

Ordering

Wt. Vol. Conc. Price
100 µg - - $385
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CASP8AP2 / FLASH Antibodies

Anti-CASP8AP2 / FLASH Antibody (N-Terminus) IHC-plus™ LS-B197
Rabbit Polyclonal
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-CASP8AP2 / FLASH Antibody (C-Terminus) IHC-plus™ LS-B198
Rabbit Polyclonal
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-CASP8AP2 / FLASH Antibody (C-Terminus) IHC-plus™ LS-B206
Rabbit Polyclonal to Human CASP8AP2 / FLASH
Human
IHC - Paraffin, ICC, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human CASP8AP2 / FLASH
Human
Western blot
Unconjugated

Details

Human CASP8AP2 / FLASH
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot

Specificity and Use

C-Terminus
Reacts with the C-terminus of the FLASH protein.
Western Blot: Use at 1:500 to 1:1000 dilution.

Packaging

PBS, pH 7.2, 0.02% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About CASP8AP2 / FLASH

Q9UKL3 NM_012115 NP_036247.1

CASP8AP2 Antibody, CASP8 associated protein 2 Antibody, CASP8-associated protein 2 Antibody, CED-4 Antibody, FLICE associated huge Antibody, FLICE-associated huge protein Antibody, KIAA1315 Antibody, FLASH Antibody, FLASH homolog RIP25 Antibody, Human FLASH Antibody, RIP25 Antibody, Caspase 8 associated protein 2 Antibody

A novel mammalian CED-4 homologous was recently identified and cloned in mouse and human and designated FLASH (for FLICE-associated huge protein). FLASH is involved in Fas induced apoptosis. It is recruited to Fas after the receptor cross-linking. Overexpression of wild type of FLASH facilitates and its dominant negative form inhibits Fas induced apoptosis. FLASH interacts with the DEDs of caspase-8 and FADD through the DED-like domain of FLASH and mediates activation of caspase-8 (1).

Requested From: United States
Date Requested: 12/5/2016

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