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Anti-CASP8 / Caspase 8 Antibody LS-C48277


Wt. Vol. Conc. Price
100 µg 200 µl 0.5 mg/ml $425
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular CASP8 / Caspase 8 Antibodies

Anti-CASP8 / Caspase 8 Antibody IHC-plus™ LS-B2225
Rabbit Polyclonal (IgG) to Human CASP8 / Caspase 8
Human, Monkey, Mouse, Rat, Bovine
IHC - Paraffin, Western blot, Immunoprecipitation
Immunohistochemistry Image
Anti-CASP8 / Caspase 8 Antibody (C-Terminus) IHC-plus™ LS-B3796
Rabbit Polyclonal to Human CASP8 / Caspase 8
Human, Mouse, Rat
IHC - Paraffin, ICC, Western blot
Immunohistochemistry Image
Anti-CASP8 / Caspase 8 Antibody (Internal, Sepharose) LS-C171973
Rabbit Polyclonal to Human CASP8 / Caspase 8
Human, Mouse, Rat
Western blot, Immunoprecipitation
Sepharose Conjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Mouse CASP8 / Caspase 8
Mouse, Rat
Western blot


Mouse CASP8 / Caspase 8
Mouse, Rat (tested or 100% immunogen sequence identity)
Affinity purified


Western blot (0.5 - 4 µg/ml)

Specificity and Use

CASP8 / Caspase 8 antibody was raised against synthetic peptide corresponding to residues surrounding amino acid 392 of mouse caspase-8.
The antibody detects the 25 kD large subunit of caspase-8. It does not detect the full-length of caspase-8.


PBS, 50% glycerol, 0.5% BSA, 0.01% Thimerosal.
Long term: -70°C; Short term: -20°C
For research use only.

About CASP8 / Caspase 8

Q14790 nm_001228 AAC50645.1

CASP8 Antibody, ALPS2B Antibody, Apoptotic protease Mch-5 Antibody, Apoptotic cysteine protease Antibody, Casp-8 Antibody, Caspase-8 Antibody, CAP4 Antibody, Caspase 8 Antibody, MACH Antibody, MCH5 Antibody, MORT1-associated ced-3 homolog Antibody, ICE-like apoptotic protease 5 Antibody, Pro Caspase 8 Antibody, FADD-like ICE Antibody, FLICE Antibody, MACH-alpha-1/2/3 protein Antibody, MACH-beta-1/2/3/4 protein Antibody

Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases.

Requested From: United States
Date Requested: 10/25/2016

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