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Anti-CASP8 / Caspase 8 Antibody (aa217-221) LS-C205388

Catalog Size Price
LS-C205388-50 50 µg (1 mg/ml) Unavailable

Most Popular CASP8 / Caspase 8 Antibodies

Anti-CASP8 / Caspase 8 Antibody (aa432-461) LS-C99287
Rabbit Polyclonal to Human CASP8 / Caspase 8
Human
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Unconjugated
Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with CASP8 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Anti-CASP8 / Caspase 8 Antibody (C-Terminus) IHC-plus™ LS-B3796
Rabbit Polyclonal (IgG) to Human CASP8 / Caspase 8
Human, Mouse, Rat
IHC, IHC - Paraffin, ICC, Western blot
Unconjugated
Anti-Caspase 8 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3796 concentration 5 ug/ml.
Anti-CASP8 / Caspase 8 Antibody (Internal, Sepharose) LS-C171973
Rabbit Polyclonal to Human CASP8 / Caspase 8
Human, Mouse, Rat
Immunoprecipitation
Sepharose Conjugated
 This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-CASP8 / Caspase 8 Antibody (clone 5F7) LS-C179764
Mouse Monoclonal [clone 5F7] (IgG2b)
Human
Western blot
Unconjugated
Western blot Image
Anti-CASP8 / Caspase 8 Antibody (phospho-Tyr380) LS-C198731
Rabbit Polyclonal (IgG) to Human CASP8 / Caspase 8
Human
Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Unconjugated
Western blot of extracts from LOVO cells treated with UV 15', using Caspase 8 (Phospho-Tyr380) Antibody. The lane on the right was incubated with synthetic peptide.

100% Guaranteed
Rabbit Polyclonal to Human CASP8 / Caspase 8
Human
Western blot
Unconjugated

Details

Human CASP8 / Caspase 8
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot (1:500 - 1:1000)

Specificity and Use

Peptide sequence around amino acids 217-221 (S-E-S-Q-T) of Caspase 8.
aa217-221
The antibody detects endogenous levels of total Caspase 8 protein.

Packaging

PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only.

About CASP8 / Caspase 8

Q14790 nm_001228 AAC50645.1

CASP8 Antibody, ALPS2B Antibody, Apoptotic protease Mch-5 Antibody, Apoptotic cysteine protease Antibody, Casp-8 Antibody, Caspase-8 Antibody, CAP4 Antibody, Caspase 8 Antibody, MACH Antibody, MCH5 Antibody, MORT1-associated ced-3 homolog Antibody, ICE-like apoptotic protease 5 Antibody, Pro Caspase 8 Antibody, FADD-like ICE Antibody, FLICE Antibody, MACH-alpha-1/2/3 protein Antibody, MACH-beta-1/2/3/4 protein Antibody

Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases.

Western blot

Western blot of extract from 293, HeLa and HT29 cells using Caspase8 antibody
Western blot of extract from 293, HeLa and HT29 cells using Caspase8 antibody

Requested From: 
Date Requested: 5/22/2018

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