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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CASP6 / Caspase 6 Antibody (Cleavage Site) IHC‑plus™ LS‑B2679
Note: This antibody replaces LS-C21311
Caspase 6 antibody LS-B2679 is an unconjugated rabbit polyclonal antibody to Caspase 6 (CASP6) from human, mouse and rabbit. Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B2679-50
50 µl (0.25 mg/ml)
Unavailable

Popular CASP6 / Caspase 6 Products

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Product Description

Caspase 6 antibody LS-B2679 is an unconjugated rabbit polyclonal antibody to Caspase 6 (CASP6) from human, mouse and rabbit. Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues.
About CASP6 / Caspase 6
Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. P55212 NM_001226 NP_001217.2

CASP6 Antibody, Apoptotic protease Mch-2 Antibody, Caspase 6 Antibody, CASP-6 Antibody, Caspase-6 Antibody, Mch-2 Antibody, MCH2 Antibody


Specifications

Target
Mouse CASP6 / Caspase 6
Host
Rabbit
Reactivity
Mouse, Human, Rabbit (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • Western blot (1:1000)
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide KLH coupled corresponding to residues surrounding the cleavage site of caspase-6.
Epitope
Cleavage Site
Specificity
Caspase-6 Antibody recognizes endogenous levels of both full length caspase-6 (35kD) and the small subunit of caspase-6 resulting from cleavage at Asp194 (15kD). This antibody does not recognize other caspases. Recognizes human, mouse, rabbit.
Usage
Immunohistochemistry: LS-B2679 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2679 was determined to be 5 ug/ml.
Presentation
10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/ml BSA, 50% glycerol. No preservative added.
Storage
4°C or -20°C, Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Immunohistochemistry

Anti-Caspase 6 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2679 concentration 5 ug/ml.
Anti-Caspase 6 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2679 concentration 5 ug/ml.

Immunohistochemistry

Anti-Caspase 6 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2679 concentration 5 ug/ml.
Anti-Caspase 6 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2679 concentration 5 ug/ml.

Immunohistochemistry

Anti-Caspase 6 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2679 concentration 5 ug/ml.
Anti-Caspase 6 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2679 concentration 5 ug/ml.

Immunohistochemistry

Anti-Caspase 6 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2679 concentration 5 ug/ml.
Anti-Caspase 6 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2679 concentration 5 ug/ml.


Requested From: 
Date Requested: 6/24/2018

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