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Anti-CASP3 / Caspase 3 Antibody (N-Terminus, AF488) LS-C12480

Ordering

Wt. Vol. Conc. Price
- 100 µl - $545
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
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Rabbit Polyclonal (IgG) to Human CASP3 / Caspase 3
Human
ICC, Immunofluorescence, Flow Cytometry, ELISA
AF488 Conjugated

Details

Human CASP3 / Caspase 3
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Alexa Fluor 488
Protein A purified

Applications

ICC (1:10), Immunofluorescence, Flow Cytometry (1:10), ELISA

Specificity and Use

CASP3 / Caspase 3 antibody was raised against synthetic peptide corresponding to amino-terminal residues adjacent to Asp175 of human caspase-3 (KLH).
N-Terminus
Detects endogenous levels of the large fragment (17/19 kD) of activated caspase-3 resulting from cleavage adjacent to aspartic acid 175. Does not recognize full length caspase-3 or other cleaved caspases. Species cross-reactivity: Mouse and rat.
Suitable for use in ELISA, Flow Cytometry, Immunocytochemistry, and Immunofluorescence. Flow Cytometry: 1:10. Immunocytochemistry: 1:10.

Packaging

PBS, pH 7.2, <0.1% sodium azide, 2.0 mg/ml BSA
Store at 4°C. Do not freeze.
For research use only.

About CASP3 / Caspase 3

P42574 NM_004346 NP_004337.2

CASP3 Antibody, Apopain Antibody, CASP-3 Antibody, Caspase-3 Antibody, CPP32B Antibody, CPP32 Antibody, Cysteine protease CPP32 Antibody, SCA-1 Antibody, SREBP cleavage activity 1 Antibody, Yama Antibody, Procaspase3 Antibody, Caspase 3 Antibody, CPP-32 Antibody, PARP cleavage protease Antibody, Protein Yama Antibody

CASP3 / Caspase 3 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme.

Requested From: United States
Date Requested: 9/28/2016

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