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CASP12 / Caspase 12
caspase 12
Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene.
| Gene Name: | caspase 12 |
| Family/Subfamily: | Protease , Cysteine C14 |
| Synonyms: | CASP12, Caspase 12 pseudogene 1, Caspase 12, CASP-12, Caspase 12 (gene/pseudogene), Inactive caspase-12, CASP12P1 |
| Target Sequences: | AF486844 CAD13032.1 Q6UXS9 |
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Neuroscience
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$440
CASP12 / Caspase 12 Rabbit anti-Mouse Polyclonal (aa100-116) Antibody
Mouse
WB
Unconjugated
100 µg/$386
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
0.1 mg/$460
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200 µl/$734
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) (Biotin) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) (FITC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) (APC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) (PE) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
CASP12 / Caspase 12 Rat Monoclonal (14F7) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$392
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa71-84) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CASP12 / Caspase 12 Rat anti-Mouse Monoclonal (aa183-205) (12G6) Antibody
Mouse
ELISA, Flo, WB
Unconjugated
100 µg/$414
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CASP12 / Caspase 12 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µg/$649
CASP12 / Caspase 12 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µg/$649
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa50-99) Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CASP12 / Caspase 12 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µg/$522
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