Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse, Human, Rat
(tested or 100% immunogen sequence identity)
IHC (2 µg/ml)
Western blot (0.5 - 2 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Synthetic peptide corresponding to amino acids within the large cleavage product of murine caspase-12 (Genbank accession CAA73532).
Recognizes mouse Caspase 12. Species cross-reactivity: human and rat.
Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 0.5-2 ug/ml. Immunohistochemistry: 2 ug/ml; Stains human heart tissue. Positive control: Human heart cell lysate.
PBS, pH 7.4, 0.02% Sodium Azide
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon.