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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CASP12 / Caspase 12 Antibody LS‑C12603
Caspase 12 antibody LS-C12603 is an unconjugated rabbit polyclonal antibody to Caspase 12 (CASP12) from human, mouse and rat. Validated for IHC and WB.
Antibody
Catalog
Size
Price
LS-C12603-100
100 µg
$515

Popular CASP12 / Caspase 12 Products

Anti-CASP12 / Caspase 12 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B747 concentration 10 ug/ml.
Species: Mouse, Human, Rat
Applications: IHC, IHC - Paraffin, Western blot
Anti-CASP12 / Caspase 12 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3785 concentration 5 ug/ml.
Species: Mouse, Human, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Western blot of caspase-12 in mouse (lane A) and rat (lane B) liver lysate with caspase-12 antibody at 1 ug/ml.
Species: Mouse, Human, Rat
Applications: IHC, Western blot
Antibody
Species: Human
Applications: IHC, ICC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Western blot of Caspase-12 in mouse skeletal muscle lysate in the 1) absence and 2) presence of immunizing peptide using LS-C148591 at 0.25 ug/ml. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution, were used for this test.
Species: Mouse
Applications: Western blot

Product Description

Caspase 12 antibody LS-C12603 is an unconjugated rabbit polyclonal antibody to Caspase 12 (CASP12) from human, mouse and rat. Validated for IHC and WB.

Specifications

Target
Mouse CASP12 / Caspase 12
Synonyms
CASP12, Caspase 12 pseudogene 1, Caspase 12, CASP-12, Caspase 12 (gene/pseudogene), Inactive caspase-12, CASP12P1
Host
Rabbit
Reactivity
Mouse, Human, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC (2 µg/ml)
  • Western blot (0.5 - 2 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide corresponding to amino acids within the large cleavage product of murine caspase-12 (Genbank accession CAA73532).
Specificity
Recognizes mouse Caspase 12. Species cross-reactivity: human and rat.
Usage
Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 0.5-2 ug/ml. Immunohistochemistry: 2 ug/ml; Stains human heart tissue. Positive control: Human heart cell lysate.
Presentation
PBS, pH 7.4, 0.02% Sodium Azide
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
About CASP12 / Caspase 12
Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. Q6UXS9 AF486844 CAD13032.1


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Requested From: United States
Date Requested: 10/21/2018

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